Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 3/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.36 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7746403 | 1.00 | GPR84 (0.42) | GPR84FFAR1MAPTFFAR4FDPS | |
| SCHEMBL6021146 | 1.00 | GPR84 (0.42) | GPR84FFAR1MAPTFFAR4FDPS | |
| SCHEMBL6743046 | 1.00 | GPR84 (0.42) | GPR84FFAR1MAPTFFAR4FDPS | |
| SCHEMBL6738137 | 1.00 | GPR84 (0.42) | GPR84FFAR1MAPTFFAR4FDPS | |
| SCHEMBL1276926 | 1.00 | GPR84 (0.42) | GPR84FFAR1MAPTFFAR4FDPS | |
| SCHEMBL8971316 | 1.00 | GPR84 (0.42) | GPR84FFAR1MAPTFFAR4FDPS | |
| SCHEMBL10703861 | 0.98 | GPR84 (0.39) | GPR84FFAR1MAPTFFAR4FDPS | |
| SCHEMBL10534735 | 0.91 | DNM1 (0.33) | GPR84FFAR1MAPTFDPSDNM1 | |
| SCHEMBL9714347 | 0.86 | MAPT (0.46) | GPR84FFAR1MAPTFDPSLMNA | |
| SCHEMBL7167398 | 0.86 | MAPT (0.46) | GPR84FFAR1MAPTFDPSLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001026671-A1 | METHODS OF TREATMENT USING DUAL MATRIX-METALLOPROTEINASE-2 AND MATRIX METALLOPROTEINASE-9 INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-04-19 | — | — | WO | disclosed |