SCHEMBL7746583

SCHEMBL7746583

CCC(O)OCCN(C)C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.42
CHRM2 P08172 4/20 0.39
CHRM1 P11229 4/20 0.39
LMNA P02545 3/20 0.39
CHRM4 P08173 3/20 0.39
CHRM5 P08912 3/20 0.39
CHRM3 P20309 3/20 0.39
ADRA2A P08913 3/20 0.39
SLC6A2 P23975 3/20 0.39
SLC6A4 P31645 3/20 0.39
OPRM1 P35372 3/20 0.39
DRD3 P35462 3/20 0.39
SLC6A3 Q01959 3/20 0.39
CYP2D6 P10635 3/20 0.39
ADRA2B P18089 2/20 0.39
HRH2 P25021 2/20 0.39
HTR2A P28223 2/20 0.39
HTR2C P28335 2/20 0.39
ADRA1A P35348 2/20 0.39
HRH1 P35367 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22503904 0.86 TSHR (0.39) TSHRKDM4ESMN1; SMN2DNM1TDP1
SCHEMBL22877646 0.85 KDM4E (0.40) TSHRLMNACYP2D6CYP1A2KDM4E
SCHEMBL1631521 0.81 CHRM2 (0.39) TSHRCHRM2CHRM1LMNACHRM4
SCHEMBL7751447 0.79 TSHR (0.40) TSHRCHRM2CHRM1LMNACHRM4
SCHEMBL4203081 0.79 CHRM2 (0.38) TSHRCHRM2CHRM1LMNACHRM4
SCHEMBL15161892 0.79 CHRM2 (0.40) TSHRCHRM2CHRM1LMNACHRM4
SCHEMBL8624149 0.78
SCHEMBL31328392 0.77 DNM1 (0.43) TSHRCHRM2CHRM1LMNACHRM4
SCHEMBL7566647 0.75 CHRM2 (0.42) TSHRCHRM2CHRM1LMNACHRM4
SCHEMBL35893 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116063344-A Modified heptamethyltrisiloxane, preparation method and application thereof 宜昌泽美新材料有限公司 2023-05-05 CN disclosed
CN-110036145-B Polyurethane elastic fiber and method for producing polyurethane elastic fiber 三光株式会社 2020-11-27 CN disclosed
US-10729775-B2 Lipids and lipid compositions for the delivery of active agents NOVARTIS AG (CH) 2020-08-04 US disclosed
CN-110036145-A The manufacturing method of polyurethane elastomeric fiber 三光株式会社 2019-07-19 CN disclosed
EP-0675412-B1 Photosensitive resin composition JAPAN SYNTHETIC RUBBER CO LTD (JP) 2001-01-17 EP disclosed
US-5861232-A FLEXOGRAPHIC PLATE NIPPON PAINT CO., LTD. (JP) 1999-01-19 US disclosed
EP-0745900-B1 Water-developing photosensitive resin composition NIPPON PAINT CO LTD (JP) 1998-12-30 EP disclosed
US-5736298-A COMPRISES A PARTICULATE POLYMER OF A CARBOXY-GROUP-CONTAINING-DIENE HAVING A CROSSLINKED STRUCTURE JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1998-04-07 US disclosed
US-5731128-A ELASTICITY, HARDNESS, ELONGATION; WATER DEVELOPABILITY NIPPON PAINT CO., LTD. (JP) 1998-03-24 US disclosed
US-5731129-A Photosensitive resin composition comprising a carboxyl group-containing diene copolymer and a hydrogenated diene block polymer JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1998-03-24 US disclosed
EP-0607962-B1 Photosensitive resin composition JAPAN SYNTHETIC RUBBER CO LTD (JP) 1996-07-17 EP disclosed
EP-0675412-A1 Photosensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1995-10-04 EP disclosed
US-5354495-A Homo- or copolymerizable through ethylenic unsaturation NIPPON PAINT CO., LTD. (JP) 1994-10-11 US disclosed
EP-0607962-A1 Photosensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1994-07-27 EP disclosed
EP-0204497-B1 Polymerisation process employing compounds having polymerisable acylurethane structures NIPPON PAINT CO LTD (JP) 1994-07-13 EP disclosed
EP-0177122-B1 ACRYLAMIDE DERIVATIVES Nippon Paint Co., Ltd. (JP) 1992-04-01 EP disclosed
US-4935413-A ELASTICITY, ADHESION AND DISPERSIBILITY NIPPON PAINT CO., LTD. (JP) 1990-06-19 US disclosed
US-4902727-A Compounds having a polymerizable acylurethane structure, and their production and process of using NIPPON PAINT CO., LTD. (JP) 1990-02-20 US disclosed
EP-0204497-A1 Polymerisation process employing compounds having polymerisable acylurethane structures Nippon Paint Co., Ltd. (JP) 1986-12-10 EP disclosed
EP-0177122-A2 Acrylamide derivatives Nippon Paint Co., Ltd. (JP) 1986-04-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10729775-B2 Lipids and lipid compositions for the delivery of active agents LIPA, LPAR1, LPAR4 TSHR 1112/4885CHRM2 2684/4885CHRM1 2163/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.