SCHEMBL774687

SCHEMBL774687

C=CCSC(=O)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11872549 0.80
SCHEMBL1457345 0.77 TRPA1 (0.42)
SCHEMBL19348074 0.77 TRPA1 (0.42)
SCHEMBL458309 0.74
SCHEMBL950500 0.74
SCHEMBL467841 0.74
SCHEMBL12989065 0.74
SCHEMBL1532458 0.74
SCHEMBL11032359 0.72
SCHEMBL5807176 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE41226-E1 Compounds having reversible inhibiting activity of carnitine palmitoyl-transferase SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) 2010-04-13 US claimed
US-RE40861-E1 Compounds having reversible inhibiting activity of carnitine palmitoyl-transferase Sigma-Tau Industrie Farmaceutiche Reunite S.p.A. (IT) 2009-07-21 US claimed
US-6444701-B1 TREATING HYPERGLYCEMIA, DIABETES AND PATHOLOGIES RELATED THERETO, HEART FAILURE, ISCHEMIA. SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) 2002-09-03 US claimed
US-6369073-B1 HYPERGLYCEMIA, DIABETES, HEART FAILURE, ISCHEMIA SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) 2002-04-09 US claimed
EP-0153127-B1 N-ARYL-3-ARYL-4,5-DIHYDRO-1H-PYRAZOLE-1-CARBOXAMIDES, PROCESSES FOR THEIR PRODUCTION, INSECTICIDAL COMPOSITIONS CONTAINING THEM AND METHODS FOR COMBATTING INSECTS ROHM AND HAAS COMPANY (US) 1991-04-03 EP claimed
EP-0153127-A2 N-aryl-3-aryl-4,5-dihydro-1H-pyrazole-1-carboxamides, processes for their production, insecticidal compositions containing them and methods for combatting insects ROHM AND HAAS COMPANY (US) 1985-08-28 EP claimed
US-4332744-A ENERGETIC ADDITIVES TO PROPELLANTS AND EXPLOSIVES THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1982-06-01 US claimed
US-4320070-A ION EXCHANGE RESIN CATALYST PPG INDUSTRIES, INC. (US) 1982-03-16 US claimed
US-4273725-A Process for preparing chlorothiolformates PPG INDUSTRIES, INC. (US) 1981-06-16 US claimed
US-4268456-A FROM A MERCAPTAN AND PHOSGENE, QUATERNARY AMMONIUM SALT CATALYST PPG INDUSTRIES, INC. (US) 1981-05-19 US claimed
US-4119659-A Production of ethyl chlorothioformate STAUFFER CHEMICAL COMPANY (US) 1978-10-10 US claimed
US-9296700-B2 Method for purifying a pyrazolinone derivative SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-03-29 US disclosed
EP-2441756-B1 METHOD FOR PURIFYING A PYRAZOLINONE DERIVATIVE SUMITOMO CHEMICAL CO (JP) 2014-05-14 EP disclosed
US-8455674-B2 Chlorothioformate manufacturing method SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-06-04 US disclosed
EP-2441756-A1 METHOD FOR PURIFYING A PYRAZOLINONE DERIVATIVE Sumitomo Chemical Company, Limited (JP) 2012-04-18 EP disclosed
US-4003909-A [(1,2,4-Oxadiazol-3-yl)phenyl]carbamic or thiocarbamic acid esters E. R. SQUIBB & SONS, INC. (US) 1977-01-18 US disclosed
US-3976470-A HERBICIDE STAUFFER CHEMICAL COMPANY (US) 1976-08-24 US disclosed
US-3973947-A 1,3,5-Triazinediones and their use as selective herbicides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-08-10 US disclosed
US-3960917-A INSECTICIDES STAUFFER CHEMICAL COMPANY (US) 1976-06-01 US disclosed
US-3951971-A SELECTIVE HERBICIDES FUCHS JULIUS JAKOB 1976-04-20 US disclosed