SCHEMBL77470

SCHEMBL77470

Cc1cc(CCO)cc(C)c1Cl

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.48
CHRM1 P11229 1/20 0.48
ALOX15 P16050 1/20 0.48
MAOA P21397 1/20 0.48
TBXA2R P21731 1/20 0.48
ADRA1A P35348 1/20 0.48
HTR2B P41595 1/20 0.48
TSHR P16473 3/20 0.42
CYP1A2 P05177 1/20 0.42
POLB P06746 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C19 P33261 1/20 0.42
TP53 P04637 1/20 0.39
MAPK1 P28482 1/20 0.39
MCL1 Q07820 3/20 0.38
BCL2L1 Q07817 2/20 0.38
TDP1 Q9NUW8 1/20 0.37
ALDH1A1 P00352 3/20 0.37
MAPT P10636 2/20 0.37
KDM4E B2RXH2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9026840 0.80 TDP1 (0.40) MAPK1TDP1ALDH1A1MAPTKDM4E
SCHEMBL8462396 0.78 PTGS1 (0.55) MAOATDP1ALDH1A1MAPTKDM4E
SCHEMBL20019870 0.77 PTGS1 (0.38) TSHRTDP1ALDH1A1MAPTKDM4E
SCHEMBL10823082 0.76 CYP3A4 (0.42) CYP3A4CHRM1ALOX15MAOATBXA2R
SCHEMBL5609864 0.76 ALDH1A1 (0.46) CYP3A4TSHRPOLBTP53TDP1
SCHEMBL15262317 0.76 TDP1 (0.37) TSHRMAPK1TDP1ALDH1A1MAPT
SCHEMBL12333663 0.76 ALDH1A1 (0.47) ALOX15TP53MCL1TDP1ALDH1A1
SCHEMBL27986390 0.76 MCL1 (0.44) CYP3A4CHRM1ALOX15MAOATBXA2R
SCHEMBL29434783 0.76 ALDH1A1 (0.47) ALOX15TP53MCL1TDP1ALDH1A1
SCHEMBL20020024 0.73 MAOA (0.39) CYP3A4CHRM1ALOX15MAOATBXA2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8129308-B2 Thermal transfer image-receiving sheet and surface condition improver FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
US-8129308-B2 Thermal transfer image-receiving sheet and surface condition improver FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
CN-100539843-C Synergistic fungicidal compositions SYNGENTA PARTICIPATIONS AG (CH) 2009-09-16 CN disclosed
US-20090087552-A1 METHOD OF PRODUCING HEAT-SENSITIVE TRANSFER IMAGE-RECEIVING SHEET FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed
US-20090087552-A1 METHOD OF PRODUCING HEAT-SENSITIVE TRANSFER IMAGE-RECEIVING SHEET FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed
EP-2042334-A2 Method of producing heat-sensitive transfer image-receiving sheet Fujifilm Corporation (JP) 2009-04-01 EP disclosed
US-20090011154-A1 THERMAL TRANSFER IMAGE-RECEIVING SHEET AND SURFACE CONDITION IMPROVER FUJIFILM CORPORATION (JP) 2009-01-08 US disclosed
US-20090011154-A1 THERMAL TRANSFER IMAGE-RECEIVING SHEET AND SURFACE CONDITION IMPROVER FUJIFILM CORPORATION (JP) 2009-01-08 US disclosed