Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | ELANE | P08246 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | PLG | P00747 | 1/20 | 0.48 |
| ▸ | CTSG | P08311 | 1/20 | 0.48 |
| ▸ | CMA1 | P23946 | 1/20 | 0.48 |
| ▸ | CTRC | Q99895 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7747008 | 0.84 | KMT2A (0.68) | KMT2AMEN1ELANEALDH1A1CYP1A2 | |
| SCHEMBL14870547 | 0.73 | ALDH1A1 (0.63) | KMT2AMEN1ELANETDP1ALDH1A1 | |
| SCHEMBL21359663 | 0.72 | KMT2A (1.00) | KMT2AMEN1ELANETDP1ALDH1A1 | |
| SCHEMBL5384563 | 0.69 | KMT2A (1.00) | KMT2AMEN1ELANEALDH1A1CYP1A2 | |
| SCHEMBL7486579 | 0.69 | CNR1 (0.59) | KMT2AMEN1ELANEALDH1A1CYP2C19 | |
| SCHEMBL8133525 | 0.69 | ELANE (0.61) | KMT2AMEN1ELANEALDH1A1F2 | |
| SCHEMBL17824459 | 0.69 | ELANE (0.61) | KMT2AMEN1ELANEALDH1A1F2 | |
| SCHEMBL20339296 | 0.68 | KMT2A (0.73) | KMT2AMEN1ELANEALDH1A1CYP1A2 | |
| SCHEMBL11453870 | 0.67 | ELANE (0.70) | KMT2AMEN1ELANETDP1ALDH1A1 | |
| SCHEMBL6620106 | 0.66 | ELANE (0.53) | KMT2AMEN1ELANEALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001027087-A2 | PROCESS FOR MAKING BOC-PROTECTED 3-AMINOHYDANTOINS/THIOHYDANTOINS AND 3-AMINODIHYDROURACILS/DIHYDROTHIOURACILS | THE PROCTER & GAMBLE COMPANY (US) | 2001-04-19 | — | — | WO | disclosed |