Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 6/20 | 0.49 |
| ▸ | ACE | P12821 | 4/20 | 0.48 |
| ▸ | CPA1 | P15085 | 4/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 10/20 | 0.45 |
| ▸ | MMP1 | P03956 | 4/20 | 0.45 |
| ▸ | MMP3 | P08254 | 4/20 | 0.45 |
| ▸ | MMP7 | P09237 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP12 | P39900 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7597065 | 0.90 | ALDH1A1 (0.52) | — | |
| SCHEMBL6904234 | 0.90 | MME (0.52) | MMEACECPA1ACE2L3MBTL1 | |
| SCHEMBL759233 | 0.90 | MME (0.52) | MMEACECPA1ACE2L3MBTL1 | |
| SCHEMBL5691576 | 0.90 | MME (0.52) | MMEACECPA1ACE2L3MBTL1 | |
| SCHEMBL4961026 | 0.83 | MME (0.49) | MMEACECPA1ACE2 | |
| SCHEMBL1081960 | 0.82 | MMP2 (0.56) | MMEACECPA1ACE2MMP2 | |
| SCHEMBL7743249 | 0.80 | NPSR1 (0.44) | MMEACECPA1ACE2L3MBTL1 | |
| SCHEMBL7602371 | 0.80 | ALDH1A1 (0.45) | MMP2MMP1MMP3 | |
| SCHEMBL4311 | 0.80 | ALDH1A1 (0.55) | — | |
| SCHEMBL12829570 | 0.80 | ALDH1A1 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001009168-A1 | A METHOD FOR THE PURIFICATION OF N-[N-(3,3-DIMETHYLBUTYL)-L-α-ASPARTYL]-L-PHENYLALANINE 1-METHYL ESTER | THE NUTRASWEET COMPANY (US) | 2001-02-08 | — | — | WO | disclosed |