Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | F11 | P03951 | 10/20 | 0.44 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.42 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4760270 | 0.91 | F11 (0.50) | F11AVPR1A | |
| SCHEMBL3276637 | 0.87 | CALCRL (0.46) | HRH3AVPR1AMAPTCALCRL | |
| SCHEMBL17205370 | 0.85 | F11 (0.55) | F11AVPR1A | |
| SCHEMBL18490941 | 0.81 | F11 (0.53) | F11 | |
| SCHEMBL17205822 | 0.81 | F11 (0.53) | F11 | |
| SCHEMBL5003859 | 0.79 | PLD2 (0.44) | F11AVPR1AKDM4EMAPTTHRB | |
| SCHEMBL2103144 | 0.76 | AVPR1A (0.50) | AVPR1AMAPTCALCRL | |
| SCHEMBL13314901 | 0.76 | CALCRL (0.50) | F11AVPR1AKDM4EMAPTCALCRL | |
| SCHEMBL10914505 | 0.76 | AVPR1A (0.50) | F11AVPR1AELOVL6 | |
| SCHEMBL13314907 | 0.74 | KCNH2 (0.56) | AVPR1AKDM4ECALCRL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001022919-A2 | SPIRO[BICYCLIC -AZACYCLOALKYL AND -CYCLOALKYL] DERIVATIVES AND USES THEREOF | MERCK & CO., INC. (US) | 2001-04-05 | — | — | WO | disclosed |