SCHEMBL7747522

SCHEMBL7747522

NC(=O)C[C@H](NC(=O)CP(=O)(O)O)C(=O)O

nearest known ligand 0.74

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CA2 P00918 6/20 0.74
CA4 P22748 1/20 0.74
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
ECE1 P42892 3/20 0.45
ITGB2 P05107 2/20 0.45
ICAM1 P05362 2/20 0.45
ITGAL P20701 2/20 0.45
CA1 P00915 4/20 0.43
OTC P00480 1/20 0.41
ENO1 P06733 1/20 0.41
ALDH1A1 P00352 1/20 0.40
RAB9A P51151 1/20 0.40
FOLH1 Q04609 1/20 0.36
MME P08473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycine SCHEMBL5497426 0.94 CA2 (0.71) CA2CA4MEN1KMT2AECE1
Pala SCHEMBL59449 0.85 CA2 (1.00) CA2CA4MEN1KMT2ACA1
Sparfosic Acid SCHEMBL3514530 0.85 CA2 (1.00) CA2CA4MEN1KMT2ACA1
Pala SCHEMBL11121904 0.84 CA2 (0.96) CA2CA4MEN1KMT2ACA1
Pala SCHEMBL31389020 0.84 CA2 (0.96) CA2CA4MEN1KMT2ACA1
Sparfosic Acid SCHEMBL31237824 0.84 CA2 (0.96) CA2CA4MEN1KMT2ACA1
Pala SCHEMBL859680 0.84 CA2 (0.96) CA2CA4MEN1KMT2ACA1
SCHEMBL13997116 0.81 CA2 (0.54) CA2CA4MEN1KMT2AECE1
SCHEMBL14521397 0.81 CA2 (0.54) CA2CA4MEN1KMT2AECE1
SCHEMBL3510048 0.77 ECE1 (0.50) CA2CA4MEN1KMT2AECE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2796112-B2 Degradable implantable medical devices ELIXIR MEDICAL CORP (US) 2023-08-09 EP claimed
EP-2796112-B1 Degradable implantable medical devices ELIXIR MEDICAL CORP (US) 2016-11-16 EP claimed
EP-0594667-B1 TREATMENT OF CHEMOTHERAPEUTIC AGENT AND ANTIVIRAL AGENT TOXICITY WITH ACYLATED PYRIMIDINE NUCLEOSIDES PRO NEURON INC (US) 2001-09-19 EP claimed
EP-0554363-B1 ALTERATION OF RATE AND CHARACTER OF HAIR GROWTH HANDELMAN JOSEPH H (US) 1998-06-24 EP claimed
US-5238955-A Anticarcinogenic agents ASTA PHARMA AG (DE) 1993-08-24 US disclosed
EP-0324154-B1 1,2 BIS(AMINOMETHYL)CYCLOBUTANE-PLATINUM-COMPLEXES ASTA Medica Aktiengesellschaft (DE) 1993-03-17 EP disclosed
US-5194644-A Antitumor agents; treatment of leukemia ASTA PHARMA AG (DE) 1993-03-16 US disclosed
US-5130308-A Indole derivatives as anticarcinogenic agents ASTA PHARMA (DE) 1992-07-14 US disclosed
EP-0204989-B1 USE OF PENICILLAMINE IN THE TREATMENT OF IMMUNE DEFICIENCY DISEASES ASTA Medica Aktiengesellschaft (DE) 1992-03-25 EP disclosed
EP-0451753-A1 In the ethylenic moiety substituted phenylalkylethylenediamine-platinum (II or IV) derivatives and phenylalkyl-ethylenediamines ASTA Medica Aktiengesellschaft (DE) 1991-10-16 EP disclosed
US-5023335-A Antitumor agents ASTA PHARMA AKTIENGESELLSCHAFT 1991-06-11 US disclosed
US-4992553-A Treatment of hormone dependent tumors ASTA PHARMA AKTIENGESELLSCHAFT (DE) 1991-02-12 US disclosed
EP-0193055-B1 ANTITUMORALS(1,2-DIPHENYL-ETHYLENE DIAMINE)-PLATINUM (II) COMPLEXES ASTA Pharma AG (DE) 1990-05-16 EP disclosed
EP-0324154-A2 1,2 Bis(aminomethyl)cyclobutane-platinum-complexes ASTA Medica Aktiengesellschaft (DE) 1989-07-19 EP disclosed
EP-0262498-A2 Diamine platinum (II) complex compounds with a hydroxy-substituted 2-phenyl-indole ring ASTA Pharma Aktiengesellschaft (DE) 1988-04-06 EP disclosed
EP-0116955-B1 COMPLEXES OF (1,2-DIPHENYL-ETHYLENE DIAMINE) PLATINUM (II) Degussa Aktiengesellschaft (DE) 1987-05-20 EP disclosed
EP-0204989-A2 Use of penicillamine in the treatment of immune deficiency diseases ASTA Medica Aktiengesellschaft (DE) 1986-12-17 EP disclosed
EP-0193083-A1 Anti-tumoral(1-arylmethyl-ethylene diamine)-platinum(II)-complexes ASTA Pharma AG (DE) 1986-09-03 EP disclosed
EP-0193055-A1 Antitumorals(1,2-diphenyl-ethylene diamine)-platinum (II) complexes ASTA Pharma AG (DE) 1986-09-03 EP disclosed
EP-0116955-A2 Complexes of (1,2-diphenyl-ethylene diamine) platinum (II) Degussa Aktiengesellschaft (DE) 1984-08-29 EP disclosed