Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 7/20 | 0.37 |
| ▸ | CA2 | P00918 | 7/20 | 0.37 |
| ▸ | CA12 | O43570 | 5/20 | 0.37 |
| ▸ | CA9 | Q16790 | 5/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.35 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.34 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.34 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3290847 | 0.82 | CA14 (0.39) | MAOAMAOBTDP1MEN1KMT2A | |
| SCHEMBL22558264 | 0.78 | TDP1 (0.55) | MAOAMAOBTDP1MEN1KMT2A | |
| SCHEMBL10688842 | 0.77 | MAOA (0.69) | MAOAMAOBTDP1MEN1KMT2A | |
| SCHEMBL18087669 | 0.77 | MAOA (0.69) | MAOAMAOBTDP1MEN1KMT2A | |
| SCHEMBL15139545 | 0.76 | MAOA (0.67) | MAOAMAOBTDP1MEN1KMT2A | |
| SCHEMBL5866373 | 0.76 | TDP1 (0.71) | MAOAMAOBTDP1MEN1KMT2A | |
| SCHEMBL146037 | 0.76 | TDP1 (0.71) | MAOAMAOBTDP1MEN1KMT2A | |
| SCHEMBL1286925 | 0.76 | TDP1 (0.71) | MAOAMAOBTDP1MEN1KMT2A | |
| SCHEMBL220281 | 0.76 | TDP1 (0.71) | MAOAMAOBTDP1MEN1KMT2A | |
| SCHEMBL964035 | 0.76 | TDP1 (0.71) | MAOAMAOBTDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070047-A2 | LIPIDS | Celltech Chiroscience Limited (GB) | 2001-01-24 | — | — | EP | disclosed |
| WO-1999052858-A2 | LIPIDS | CELLTECH THERAPEUTICS LIMITED (GB) | 1999-10-21 | — | — | WO | disclosed |