Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 2/20 | 0.31 |
| ▸ | CA5A | P35218 | 2/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5670996 | 0.78 | CA2 (0.40) | CA2ALDH1A1TGM2POLBSMN1; SMN2 | |
| SCHEMBL20100335 | 0.75 | TSHR (0.41) | ALDH1A1TSHRMAPK1TDP1TGM2 | |
| SCHEMBL15680116 | 0.75 | CA2 (0.37) | CA2ALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL26217 | 0.74 | — | — | |
| SCHEMBL2053132 | 0.74 | CA2 (0.59) | CA2ALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL7165464 | 0.74 | — | — | |
| Ethylene SCHEMBL8621311 | 0.72 | TSHR (0.50) | ALDH1A1TSHRMAPK1TDP1TGM2 | |
| Formaldehyde SCHEMBL16146046 | 0.72 | TSHR (0.50) | ALDH1A1TSHRMAPK1TDP1TGM2 | |
| SCHEMBL3284715 | 0.72 | TSHR (0.50) | ALDH1A1TSHRMAPK1TDP1TGM2 | |
| Methane SCHEMBL9845065 | 0.72 | TSHR (0.50) | ALDH1A1TSHRMAPK1TDP1TGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1040116-A4 | FUNCTIONALIZED PYRIMIDINE DERIVATIVES | SCRIPPS RESEARCH INST (US) | 2001-10-31 | — | — | EP | disclosed |
| US-6175001-B1 | DERIVATIZED AT C5 TO CONTAIN FUNCTIONAL GROUP THAT MIMICS THE PROPERTY OF NATURALLY OCCURRING AMINO ACID; FOR USE IN POLYMERASE CHAIN REACTIONS | THE SCRIPPS RESEARCH INSTITUTE | 2001-01-16 | — | — | US | disclosed |
| EP-1040116-A1 | FUNCTIONALIZED PYRIMIDINE DERIVATIVES | The Scripps Research Institute (US) | 2000-10-04 | — | — | EP | disclosed |
| WO-2000052192-A1 | ENZYMATIC DNA MOLECULES THAT CONTAIN MODIFIED NUCLEOTIDES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2000-09-08 | — | — | WO | disclosed |
| US-6110462-A | NUCLEOTIDE CATALYSTS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2000-08-29 | — | — | US | disclosed |
| WO-2000023456-A1 | FUNCTIONALIZED PYRIMIDINE DERIVATIVES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2000-04-27 | — | — | WO | disclosed |
| EP-0330221-B1 | End labeled nuceotide probe | ENZO BIOCHEM INC (US) | 1997-10-29 | — | — | EP | disclosed |
| EP-0783000-A2 | Method for synthesizing end labeled nucleotide probes | ENZO BIOCHEM, INC. (US) | 1997-07-09 | — | — | EP | disclosed |
| US-5082830-A | Sequence determination, nonradioactive | ENZO BIOCHEM, INC. (US) | 1992-01-21 | — | — | US | disclosed |
| EP-0330221-A2 | End labeled nuceotide probe | ENZO BIOCHEM, INC. (US) | 1989-08-30 | — | — | EP | disclosed |