Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 8/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | AOC2 | O75106 | 5/20 | 0.40 |
| ▸ | MAOA | P21397 | 5/20 | 0.40 |
| ▸ | MAOB | P27338 | 5/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6591026 | 0.82 | CA2 (0.56) | CA2CA1NISCH | |
| SCHEMBL7477080 | 0.82 | CA2 (0.40) | CA2CA1AOC2MAOAMAOB | |
| SCHEMBL5981402 | 0.81 | HPGD (0.40) | CA2CA1AOC2MAOAMAOB | |
| SCHEMBL11072331 | 0.81 | HPGD (0.43) | CA2AOC2MAOAMAOBDAO | |
| SCHEMBL30084102 | 0.81 | HPGD (0.40) | CA2CA1AOC2MAOAMAOB | |
| SCHEMBL10840184 | 0.79 | SMN1; SMN2 (0.50) | CA2CA1MAOAMAOBTSHR | |
| SCHEMBL28897275 | 0.75 | CA2 (0.38) | CA2CA1AOC2MAOAMAOB | |
| SCHEMBL5864109 | 0.74 | CA2 (0.54) | CA2CA1NISCH | |
| SCHEMBL30132282 | 0.73 | HPGD (0.34) | CA2CA1AOC2MAOAMAOB | |
| SCHEMBL18208033 | 0.70 | NISCH (0.43) | CA2HPGDNISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4906287-A | Herbicidal compounds | FMC CORPORATION (US) | 1990-03-06 | — | — | US | claimed |
| EP-0929540-A4 | ANTITUMOR COMPOSITIONS AND METHODS OF TREATMENT | LILLY CO ELI (US) | 2001-12-12 | — | — | EP | disclosed |
| EP-0929540-A1 | ANTITUMOR COMPOSITIONS AND METHODS OF TREATMENT | ELI LILLY AND COMPANY (US) | 1999-07-21 | — | — | EP | disclosed |
| US-5827879-A | SUBSTITUTED 2,3-DIHYDROBENOFURYL SULFONAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1998-10-27 | — | — | US | disclosed |
| WO-1998014440-A1 | ANTITUMOR COMPOSITIONS AND METHODS OF TREATMENT | ELI LILLY AND COMPANY (US) | 1998-04-09 | — | — | WO | disclosed |
| EP-0173899-B1 | 2,3-DIHYDROBENZOFURAN-5-SULFONAMIDE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 1991-12-18 | — | — | EP | disclosed |
| US-4659709-A | LESS ADVERSE SIDE-EFFECTS | SHIONOGI & CO. (JP) | 1987-04-21 | — | — | US | disclosed |
| EP-0173899-A2 | 2,3-Dihydrobenzofuran-5-sulfonamide derivatives | SHIONOGI & CO., LTD. (JP) | 1986-03-12 | — | — | EP | disclosed |
| EP-0123303-A1 | Dihydro-benzofuran derivatives having herbicide activity | Montedison S.p.A. (IT) | 1984-10-31 | — | — | EP | disclosed |