Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 10/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 6/20 | 0.32 |
| ▸ | MAOB | P27338 | 6/20 | 0.32 |
| ▸ | AOC2 | O75106 | 5/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7748074 | 0.82 | CA2 (0.44) | CA2CA1PTGES2MAOAMAOB | |
| SCHEMBL10664459 | 0.79 | MEN1 (0.36) | CA2CA1TP53MAOAMAOB | |
| SCHEMBL11043380 | 0.75 | HRH3 (0.36) | CA2MAOAMAOBAOC2DAO | |
| SCHEMBL1081936 | 0.73 | PSEN1 (0.39) | — | |
| SCHEMBL449445 | 0.72 | MAOA (0.37) | MAOAMAOBAOC2DAOHPGD | |
| SCHEMBL1890900 | 0.72 | MAOA (0.37) | MAOAMAOBAOC2DAO | |
| SCHEMBL5215909 | 0.70 | HPGD (0.45) | MAOAMAOBAOC2DAOHPGD | |
| SCHEMBL5572317 | 0.70 | MAOA (0.38) | MAOAMAOBAOC2DAOHPGD | |
| SCHEMBL10840184 | 0.69 | SMN1; SMN2 (0.50) | CA2CA1MAOAMAOBTSHR | |
| SCHEMBL6591026 | 0.69 | CA2 (0.56) | CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861249-A1 | SUBSTITUTED SULFONYLALKANOYLAMINO HYDROXYETHYLAMINO SULFONAMIDE RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1998-09-02 | — | — | EP | disclosed |
| WO-1997018205-A1 | SUBSTITUTED SULFONYLALKANOYLAMINO HYDROXYETHYLAMINO SULFONAMIDE RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1997-05-22 | — | — | WO | disclosed |
| US-4746358-A | PLANT GROWTH REGULATORS, HERBICIDES; N-TRIAZINYL-AMINOCARBONYL -1,4-BENZODIOXANESULFONAMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-05-24 | — | — | US | disclosed |
| US-4659368-A | HERBICIDES; PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-04-21 | — | — | US | disclosed |
| US-4595407-A | Triazinyl-amino-carbonyl-1,3-benzohetero- or -1,4-benzohetero-sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-06-17 | — | — | US | disclosed |
| US-4502882-A | HERBICIDES, PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-03-05 | — | — | US | disclosed |