Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 8/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.39 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7367751 | 0.98 | AVPR2 (0.40) | AVPR2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7374551 | 0.97 | AVPR2 (0.40) | AVPR2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7373631 | 0.93 | NAMPT (0.43) | AVPR2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7748371 | 0.91 | F10 (0.38) | AVPR2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7371827 | 0.91 | AVPR2 (0.42) | AVPR2ALDH1A1AVPR1AAVPR1B | |
| SCHEMBL7748724 | 0.91 | AVPR2 (0.42) | AVPR2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7376078 | 0.90 | AVPR2 (0.42) | AVPR2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7374590 | 0.90 | AVPR2 (0.44) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL7370995 | 0.89 | AVPR2 (0.48) | AVPR2AVPR1AAVPR1BMEN1KMT2A | |
| SCHEMBL7368219 | 0.89 | L3MBTL1 (0.45) | ALDH1A1NAMPTMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211242-B1 | CARDIOVASCULAR DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-0757670-B1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-01-13 | — | — | EP | disclosed |
| WO-1995029152-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-02 | — | — | WO | disclosed |