SCHEMBL7748652

SCHEMBL7748652

C=C[Si](OC(C)=O)(OC(C)=O)OC(C)=O.CCO[Si](OCC)(c1ccccc1)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.38
ALDH1A1 P00352 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
PTGS2 P35354 5/20 0.32
PIN1 Q13526 2/20 0.32
TSHR P16473 2/20 0.31
GLA P06280 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11224422 0.85 MAPT (0.40) MAPTALDH1A1MEN1KMT2APTGS2
SCHEMBL19858500 0.79 MAPT (0.36) MAPTALDH1A1MEN1KMT2APTGS2
Methacrylic Acid SCHEMBL10788963 0.79 MAPT (0.40) MAPTALDH1A1MEN1KMT2APIN1
Methacrylic Acid SCHEMBL10711923 0.79 MAPT (0.40) MAPTALDH1A1MEN1KMT2APIN1
SCHEMBL11513444 0.78 ALDH1A1 (0.34) ALDH1A1
SCHEMBL28039741 0.76 ALDH1A1 (0.33) ALDH1A1
SCHEMBL15841389 0.76 ALDH1A1 (0.36) ALDH1A1TSHR
SCHEMBL15841434 0.76 ALDH1A1 (0.36) ALDH1A1TSHR
SCHEMBL34937 0.76 LTA4H (0.37) MAPTALDH1A1PIN1TSHRGLA
Phosphine SCHEMBL23931373 0.74 LTA4H (0.35) MAPTALDH1A1PIN1TSHRGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001009249-A1 MOISTURE CURABLE ACRYLIC SEALANTS SCHNEE-MOREHEAD, INC. (US) 2001-02-08 WO disclosed