SCHEMBL7748667

SCHEMBL7748667

COc1ccccc1S(=O)(=O)N[C@@H](CNC(=O)C1CCCN(C(=O)CCC2CCNCC2)C1)C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 19/20 0.64
ITGA2B P08514 19/20 0.64
F2R P25116 10/20 0.57
ITGAV P06756 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7501484 0.87 ITGB3 (0.68) ITGB3ITGA2BF2R
SCHEMBL7748663 0.87 ITGB3 (0.61) ITGB3ITGA2BF2R
SCHEMBL7748747 0.83 ITGB3 (0.47) ITGB3ITGA2BF2R
Hydrochloric Acid SCHEMBL7507317 0.81 ITGB3 (0.59) ITGB3ITGA2BF2R
SCHEMBL6538729 0.80 ITGB3 (0.68) ITGB3ITGA2BF2R
SCHEMBL7503852 0.80 ITGB3 (0.54) ITGB3ITGA2BF2R
SCHEMBL7452081 0.80 ITGB3 (0.75) ITGB3ITGA2BF2R
SCHEMBL7754725 0.80 ITGAV (0.56) ITGB3ITGA2BITGAV
SCHEMBL1727238 0.79 ITGB3 (0.75) ITGB3ITGA2BF2R
SCHEMBL6539304 0.79 ITGB3 (0.80) ITGB3ITGA2BF2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0725059-B1 2,3-DIAMINOPROPIONIC ACID DERIVATIVE SUMITOMO PHARMA (JP) 2001-01-17 EP disclosed
US-6048854-A ANTICOAGULANTS; ANTICANCER AGENT; WOUND HEALING AGENTS;BONE DISORDERS SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 2000-04-11 US disclosed
US-5707994-A USEFUL AS A PLATELET AGGREGATION INHIBITOR, CANCER METASTASIS INHIBITOR, WOUND HEALING AGENT OR A BONE RESORPTION INHIBITOR SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1998-01-13 US disclosed
EP-0725059-A1 2,3-DIAMINOPROPIONIC ACID DERIVATIVE SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1996-08-07 EP disclosed