Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.47 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.43 |
| ▸ | MYC | P01106 | 2/20 | 0.43 |
| ▸ | MAX | P61244 | 2/20 | 0.43 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
| ▸ | APLNR | P35414 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.40 |
| ▸ | F2R | P25116 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7753413 | 0.93 | APLNR (0.45) | TGFBR1STSAPLNRALDH1A1MEN1 | |
| SCHEMBL7494534 | 0.90 | ITGB3 (0.51) | ITGB3ITGA2BTGFBR1MYCMAX | |
| SCHEMBL7748745 | 0.88 | STS (0.51) | ITGB3ITGA2BMYCMAXSTS | |
| SCHEMBL7503852 | 0.83 | ITGB3 (0.54) | ITGB3ITGA2BTGFBR1MYCMAX | |
| SCHEMBL7748667 | 0.83 | ITGB3 (0.64) | ITGB3ITGA2BF2R | |
| SCHEMBL7498836 | 0.83 | ITGB3 (0.54) | ITGB3ITGA2BALDH1A1F2R | |
| SCHEMBL7754664 | 0.82 | ALDH1A1 (0.48) | ITGB3ITGA2BSTSALDH1A1KMT2A | |
| SCHEMBL7508442 | 0.82 | ITGB3 (0.45) | ITGB3ITGA2BMYCMAXF2R | |
| SCHEMBL7503244 | 0.82 | ITGB3 (0.50) | ITGB3ITGA2BALDH1A1F2R | |
| SCHEMBL6936056 | 0.81 | ITGB3 (0.69) | ITGB3ITGA2BALDH1A1F2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0725059-B1 | 2,3-DIAMINOPROPIONIC ACID DERIVATIVE | SUMITOMO PHARMA (JP) | 2001-01-17 | — | — | EP | disclosed |
| US-6048854-A | ANTICOAGULANTS; ANTICANCER AGENT; WOUND HEALING AGENTS;BONE DISORDERS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2000-04-11 | — | — | US | disclosed |
| US-5707994-A | USEFUL AS A PLATELET AGGREGATION INHIBITOR, CANCER METASTASIS INHIBITOR, WOUND HEALING AGENT OR A BONE RESORPTION INHIBITOR | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-01-13 | — | — | US | disclosed |
| EP-0725059-A1 | 2,3-DIAMINOPROPIONIC ACID DERIVATIVE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1996-08-07 | — | — | EP | disclosed |