Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.49 |
| ▸ | LMNA | P02545 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | POLB | P06746 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 11/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.45 |
| ▸ | HTT | P42858 | 7/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7748672 | 1.00 | MAPT (0.49) | MAPTKDM4ELMNAALDH1A1POLB | |
| Acetic Acid SCHEMBL915590 | 0.94 | MAPT (0.47) | MAPTKDM4ELMNAALDH1A1POLB | |
| Acetic Acid SCHEMBL915591 | 0.94 | MAPT (0.47) | MAPTKDM4ELMNAALDH1A1POLB | |
| SCHEMBL915592 | 0.83 | MAPT (0.46) | MAPTKDM4ELMNAALDH1A1POLB | |
| SCHEMBL7748807 | 0.82 | MEN1 (0.55) | MAPTKDM4ELMNAALDH1A1POLB | |
| SCHEMBL7748805 | 0.82 | MEN1 (0.55) | MAPTKDM4ELMNAALDH1A1POLB | |
| SCHEMBL13673683 | 0.80 | HTT (0.47) | MAPTKDM4ELMNAALDH1A1POLB | |
| SCHEMBL13673686 | 0.80 | HTT (0.47) | MAPTKDM4ELMNAALDH1A1POLB | |
| SCHEMBL916658 | 0.76 | ALDH1A1 (0.40) | MAPTKDM4ELMNAALDH1A1POLB | |
| SCHEMBL916659 | 0.76 | ALDH1A1 (0.40) | MAPTKDM4ELMNAALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001025192-A1 | GUANIDINE DERIVATIVES AND THEIR USE IN THE PRODUCTION OF A MEDICAMENT FOR BLOCKING XANTHINE OXIDASE/DEHYDROGENASE | MELACURE THERAPEUTICS AB (SE) | 2001-04-12 | — | — | WO | claimed |