Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.50 |
| ▸ | BAD | Q92934 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.39 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | GALR1 | P47211 | 1/20 | 0.38 |
| ▸ | LPL | P06858 | 1/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL239776 | 0.90 | — | — | |
| SCHEMBL14677847 | 0.83 | ALDH1A1 (0.38) | BCL2L1CA2CA9ALDH1A1 | |
| SCHEMBL12562793 | 0.83 | BCL2L1 (0.55) | BCL2L1BADPTPN1MAOBNPC1 | |
| SCHEMBL197346 | 0.83 | BCL2L1 (0.55) | BCL2L1BADPTPN1MAOBNPC1 | |
| SCHEMBL10337645 | 0.83 | BCL2L1 (0.55) | BCL2L1BADPTPN1MAOBNPC1 | |
| SCHEMBL10300262 | 0.83 | BCL2L1 (0.55) | BCL2L1BADPTPN1MAOBNPC1 | |
| Formaldehyde SCHEMBL29071812 | 0.80 | BCL2L1 (0.55) | BCL2L1BADPTPN1MAOBNPC1 | |
| SCHEMBL29256311 | 0.76 | BCL2L1 (0.50) | BCL2L1BADPTPN1MAOBNPC1 | |
| SCHEMBL522432 | 0.75 | HSPB1 (0.54) | CES2CES1KDM4EALDH1A1 | |
| SCHEMBL2944704 | 0.73 | BCL2L1 (0.48) | BCL2L1BADPTPN1MAOBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034198-A2 | ONCOLYTIC COMBINATIONS FOR THE TREATMENT OF CANCER | ELI LILLY AND COMPANY (US) | 2001-05-17 | — | — | WO | claimed |