Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.58 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.58 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.58 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.58 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.58 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.58 |
| ▸ | KLK7 | P49862 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17365594 | 1.00 | POLB (0.66) | POLBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL11487355 | 0.89 | MAPT (0.72) | POLBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL14599718 | 0.89 | MAPT (0.72) | POLBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL7823011 | 0.88 | POLB (0.53) | POLBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL16307627 | 0.88 | MAPT (0.63) | POLBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL7822974 | 0.88 | PSEN1 (0.59) | POLBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9445675 | 0.86 | PSEN1 (0.54) | POLBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL18852431 | 0.85 | ALDH1A1 (0.66) | POLBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL2165476 | 0.85 | PSEN1 (0.53) | POLBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL7795343 | 0.85 | KLK7 (0.67) | POLBALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113831301-B | Benzothiazole derivative and application thereof | 沈阳药科大学 | 2023-06-06 | — | — | CN | claimed |
| JP-7309822-A | — | — | None | — | — | JP | disclosed |
| EP-1791901-B1 | STABILIZATION OF ORGANIC MATERIALS | BASF SE (DE) | 2018-03-28 | — | — | EP | disclosed |
| EP-2685982-B1 | PYRROLOPYRIDAZINE JAK3 INHIBITORS AND THEIR USE FOR THE TREATMENT OF INFLAMMATORY AND AUTOIMMUNE DISEASES | BRISTOL MYERS SQUIBB CO (US) | 2017-07-05 | — | — | EP | disclosed |
| US-9221826-B2 | Pyrrolopyridazine JAK3 inhibitors and their use for the treatment of inflammatory and autoimmune diseases | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-12-29 | — | — | US | disclosed |
| EP-1480941-B1 | UREA DERIVATIVES AS HIV ASPARTYL PROTEASE INHIBITORS | AMBRILIA BIOPHARMA INC (CA) | 2011-01-26 | — | — | EP | disclosed |
| CN-100347202-C | Process for production of living-radical polymers and polymers | OTSUKA CHEMICAL CO LTD (JP) | 2007-11-07 | — | — | CN | disclosed |
| CN-101029117-A | Process for production of living radical polymers and polymers obtained therefrom | OTSUKA CHEMICAL CO LTD (JP) | 2007-09-05 | — | — | CN | disclosed |
| CN-1308352-C | Method for producing living radical polymer and polymer | OTSUKA CHEMICAL CO LTD (JP) | 2007-04-04 | — | — | CN | disclosed |
| CN-1780860-A | Method for producing living radical polymer and polymer | OTSUKA CHEMICAL CO LTD (JP) | 2006-05-31 | — | — | CN | disclosed |
| CN-1675253-A | Method for producing living radical polymer and polymer | OTSUKA CHEMICAL CO LTD (JP) | 2005-09-28 | — | — | CN | disclosed |
| US-6528532-B1 | Benzenesulfonamide group | PHARMACOR INC. (CA) | 2003-03-04 | — | — | US | disclosed |
| US-6528532-B1 | Benzenesulfonamide group | PHARMACOR INC. (CA) | 2003-03-04 | — | — | US | disclosed |
| JP-H07309822-A | PHENYLPROPIONANILIDE DERIVATIVE | ASAHI CHEM IND CO LTD | 1995-11-28 | — | — | JP | disclosed |