Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.72 |
| ▸ | LMNA | P02545 | 3/20 | 0.72 |
| ▸ | HTT | P42858 | 3/20 | 0.72 |
| ▸ | MEN1 | O00255 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.60 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.60 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.60 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.60 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.60 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.60 |
| ▸ | HTR1E | P28566 | 1/20 | 0.58 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | CASR | P41180 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14599718 | 1.00 | MAPT (0.72) | MAPTALDH1A1LMNAHTTMEN1 | |
| SCHEMBL14135290 | 0.91 | MAPT (0.65) | MAPTALDH1A1LMNAHTTMEN1 | |
| SCHEMBL17365594 | 0.89 | POLB (0.66) | MAPTALDH1A1LMNAHTTMEN1 | |
| SCHEMBL7748974 | 0.89 | POLB (0.66) | MAPTALDH1A1LMNAHTTMEN1 | |
| SCHEMBL7822974 | 0.85 | PSEN1 (0.59) | MAPTALDH1A1LMNAHTTMEN1 | |
| SCHEMBL9445675 | 0.83 | PSEN1 (0.54) | MAPTALDH1A1LMNAHTTMEN1 | |
| SCHEMBL15434432 | 0.83 | MAPT (0.56) | MAPTALDH1A1LMNAHTTMEN1 | |
| SCHEMBL27357989 | 0.83 | HDAC1 (0.69) | MAPTALDH1A1LMNAHTTMEN1 | |
| SCHEMBL18086477 | 0.83 | ALDH1A1 (0.65) | MAPTALDH1A1LMNAHTTMEN1 | |
| SCHEMBL7795343 | 0.82 | KLK7 (0.67) | ALDH1A1LMNAHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0008532-A1 | Synthesis of amines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-03-05 | — | — | EP | disclosed |