SCHEMBL7748992

SCHEMBL7748992

CCOC(C)OCC(=O)S

nearest known ligand 0.55

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.55
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7762904 0.79 LMNA (0.57) LMNATHRB
SCHEMBL3363687 0.79 LMNA (0.57) LMNATHRB
Bicarbonate SCHEMBL5374586 0.78 LMNA (0.71) LMNATHRB
Bicarbonate SCHEMBL28895866 0.78 LMNA (0.71) LMNATHRB
Bicarbonate SCHEMBL28942687 0.78 LMNA (0.71) LMNATHRB
Acetone SCHEMBL590699 0.78 LMNA (0.71) LMNATHRB
SCHEMBL5243851 0.77 LMNA (0.55) LMNATHRB
SCHEMBL6053363 0.77 LMNA (0.55) LMNATHRB
SCHEMBL9854567 0.77 LMNA (0.55) LMNATHRB
SCHEMBL27464187 0.76 LMNA (0.52) LMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0776322-B1 METHOD FOR THE PREPARATION OF TAXOL AND ITS DERIVATIVES PHARMACIA & UPJOHN SPA (IT) 2001-11-07 EP disclosed
EP-1116718-A2 Method for the preparation of taxol and its derivatives PHARMACIA & UPJOHN S.p.A. (IT) 2001-07-18 EP disclosed
US-5767282-A Method for the preparation of taxol and its derivatives PHARMACIA & UPJOHN S.P.A. (IT) 1998-06-16 US disclosed
EP-0776322-A1 METHOD FOR THE PREPARATION OF TAXOL AND ITS DERIVATIVES PHARMACIA & UPJOHN S.p.A. (IT) 1997-06-04 EP disclosed
WO-1997000870-A1 METHOD FOR THE PREPARATION OF TAXOL AND ITS DERIVATIVES PHARMACIA & UPJOHN S.P.A. (IT) 1997-01-09 WO disclosed