Parachlorophenol

Parachlorophenol

SCHEMBL7749035

Oc1ccc(Cl)cc1.Oc1cccc(Cl)c1

nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.81
HSD17B10 Q99714 3/20 0.50
ALDH1A1 P00352 3/20 0.50
CA12 O43570 1/20 0.50
CA2 P00918 1/20 0.50
LMNA P02545 1/20 0.50
CYP3A4 P08684 1/20 0.50
CA5A P35218 1/20 0.50
CA9 Q16790 1/20 0.50
CA14 Q9ULX7 1/20 0.50
CA5B Q9Y2D0 1/20 0.50
ESR1 P03372 3/20 0.48
ESR2 Q92731 3/20 0.48
HSD17B1 P14061 1/20 0.48
HSD17B2 P37059 1/20 0.48
MAPK1 P28482 2/20 0.46
HPGD P15428 1/20 0.43
ALOX15 P16050 1/20 0.43
ALOX12 P18054 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29395743 0.90
SCHEMBL49772 0.90
Phenol SCHEMBL5544839 0.88 TSHR (0.85) TSHRHSD17B10ALDH1A1CA12CA2
Iodide SCHEMBL2427781 0.87
SCHEMBL27597768 0.87
SCHEMBL7386386 0.87
Hydrochloric Acid SCHEMBL28884152 0.87
Parachlorophenol SCHEMBL27814172 0.87 TSHR (0.61) TSHRHSD17B10ALDH1A1CA12CA2
Bromide SCHEMBL11041612 0.85 TSHR (0.90) TSHRHSD17B10ALDH1A1CA12CA2
Methyl Alcohol SCHEMBL27366348 0.85 TSHR (0.90) TSHRHSD17B10ALDH1A1CA12CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2948256-B1 ANTISEPTIC APPLICATOR CAREFUSION 2200 INC (US) 2022-12-14 EP disclosed
US-11008276-B2 Processes for preparing 2,5-dichlorophenol MONSANTO TECHNOLOGY LLC (US) 2021-05-18 US disclosed
EP-3201164-B1 PROCESSES FOR PREPARING 2,5-DICHLOROPHENOL MONSANTO TECHNOLOGY LLC (US) 2020-11-25 EP disclosed
US-20200216379-A1 PROCESSES FOR PREPARING 2,5-DICHLOROPHENOL MONSANTO TECHNOLOGY LLC (US) 2020-07-09 US disclosed
US-10550063-B2 Processes for preparing 2,5-dichlorophenol MONSANTO TECHNOLOGY LLC (US) 2020-02-04 US disclosed
US-20170247310-A1 PROCESSES FOR PREPARING 2,5-DICHLOROPHENOL MONSANTO TECHNOLOGY LLC (US) 2017-08-31 US disclosed
EP-3201164-A1 PROCESSES FOR PREPARING 2,5-DICHLOROPHENOL Monsanto Technology LLC (US) 2017-08-09 EP disclosed
CN-107001211-A Process for preparing 2, 5-dichlorophenol 孟山都技术公司 2017-08-01 CN disclosed
WO-2016054506-A1 PROCESSES FOR PREPARING 2,5-DICHLOROPHENOL MONSANTO TECHNOLOGY LLC (US) 2016-04-07 WO disclosed
EP-2948256-A1 ANTISEPTIC APPLICATOR CareFusion 2200 Inc. (US) 2015-12-02 EP disclosed
WO-2014116482-A1 ANTISEPTIC APPLICATOR CAREFUSION 2200, INC. (US) 2014-07-31 WO disclosed
WO-2001032911-A2 TOXICITY ASSAY USING PVA-IMMOBILISED LUMINESCENT BACTERIA THE COURT OF NAPIER UNIVERSITY (GB) 2001-05-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200216379-A1 PROCESSES FOR PREPARING 2,5-DICHLOROPHENOL HPD, DDT, HAO2 TSHR 3869/4885HSD17B10 533/4885ALDH1A1 485/4885
US-20170247310-A1 PROCESSES FOR PREPARING 2,5-DICHLOROPHENOL HPD, DDT, HAO2 TSHR 3869/4885HSD17B10 533/4885ALDH1A1 485/4885
US-10550063-B2 Processes for preparing 2,5-dichlorophenol HPD, DDT, HAO2 TSHR 3869/4885HSD17B10 533/4885ALDH1A1 485/4885
US-11008276-B2 Processes for preparing 2,5-dichlorophenol HPD, DDT, HAO2 TSHR 3869/4885HSD17B10 533/4885ALDH1A1 485/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.