SCHEMBL7749073

SCHEMBL7749073

CCCCCCCCCC(=O)F

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 5/20 0.62
CES1 P23141 5/20 0.62
GPR84 Q9NQS5 7/20 0.59
PPARG P37231 7/20 0.59
PPARD Q03181 7/20 0.59
PPARA Q07869 7/20 0.59
HDAC11 Q96DB2 5/20 0.59
TSHR P16473 5/20 0.59
PTPN1 P18031 3/20 0.59
ALDH1A1 P00352 3/20 0.59
TLR2 O60603 2/20 0.59
TDP1 Q9NUW8 2/20 0.59
FABP4 P15090 2/20 0.59
SLC22A6 Q4U2R8 1/20 0.59
SLC22A8 Q8TCC7 1/20 0.59
MEN1 O00255 1/20 0.59
ESR1 P03372 1/20 0.59
ALOX15 P16050 1/20 0.59
PDE4A P27815 1/20 0.59
KMT2A Q03164 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27564098 1.00 CES2 (0.62) CES2CES1GPR84PPARGPPARD
SCHEMBL25947206 1.00 CES2 (0.62) CES2CES1GPR84PPARGPPARD
SCHEMBL27528985 1.00 CES2 (0.62) CES2CES1GPR84PPARGPPARD
SCHEMBL17742313 1.00 CES2 (0.62) CES2CES1GPR84PPARGPPARD
SCHEMBL5701258 1.00 CES2 (0.62) CES2CES1GPR84PPARGPPARD
SCHEMBL2326471 1.00 CES2 (0.62) CES2CES1GPR84PPARGPPARD
SCHEMBL30991864 1.00 CES2 (0.62) CES2CES1GPR84PPARGPPARD
SCHEMBL8590718 1.00 CES2 (0.62) CES2CES1GPR84PPARGPPARD
SCHEMBL2336034 1.00 CES2 (0.62) CES2CES1GPR84PPARGPPARD
SCHEMBL8344152 1.00

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0967965-A4 LOW FOAMING THERAPEUTIC TOOTHPASTES WITH IMPROVED CLEANING AND ABRASION PERFORMANCE WHITEHILL ORAL TECH INC (US) 2001-01-24 EP disclosed
EP-0967965-A1 LOW FOAMING THERAPEUTIC TOOTHPASTES WITH IMPROVED CLEANING AND ABRASION PERFORMANCE WHITEHILL ORAL TECHNOLOGIES INC. (US) 2000-01-05 EP disclosed
US-5993784-A Low foaming therapeutic toothpastes with improved cleaning and abrasion performance WHITEHILL ORAL TECHNOLOGIES (US) 1999-11-30 US disclosed
US-5753776-A PERFLUORINATION HYDROGEN CONTAINING COMPOUNDS EXFLUOR RESEARCH CORPORATION (US) 1998-05-19 US disclosed
WO-1998004234-A1 LOW FOAMING THERAPEUTIC TOOTHPASTES WITH IMPROVED CLEANING AND ABRASION PERFORMANCE WHITEHILL ORAL TECHNOLOGIES, INC. (US) 1998-02-05 WO disclosed
US-5674949-A Liquid-phase fluorination EXFLUOR RESEARCH CORPORATION (US) 1997-10-07 US disclosed
US-5571870-A Liquid phase fluorination EXFLUOR RESEARCH CORPORATION (US) 1996-11-05 US disclosed
US-5461117-A Perfluorination of hydrogen-containing compound in liquid perhalogenated medium with fluorine gas; with little oligomerization or polymerization EXFLUOR RESEARCH CORPORATION (US) 1995-10-24 US disclosed
CN-1106077-A Process for preparating fluorochemicals MINNESOTA MINING & MFG (US) 1995-08-02 CN disclosed
EP-0441807-B1 LIQUID PHASE FLUORINATION EXFLUOR RES CORP (US) 1995-03-22 EP disclosed
US-5332790-A Liquid-phase fluorination EXFLUOR RESEARCH CORPORATION (US) 1994-07-26 US disclosed
US-5322904-A Liquid-phase fluorination EXFLUOR RESEARCH CORPORATION (US) 1994-06-21 US disclosed
US-5322903-A Liquid-phase fluorination EXFLUOR RESEARCH CORPORATION (US) 1994-06-21 US disclosed
US-5093432-A Perfluorination of esters or ethers EXFLUOR RESEARCH CORPORATION (US) 1992-03-03 US disclosed
EP-0441807-A1 LIQUID PHASE FLUORINATION. EXFLUOR RES CORP (US) 1991-08-21 EP disclosed
WO-1990003353-A1 LIQUID PHASE FLUORINATION EXFLUOR RESEARCH CORPORATION (US) 1990-04-05 WO disclosed