SCHEMBL7749124

SCHEMBL7749124

CCCCCCCCCCCCCCCCCC(C)SC(C)CCCCCCCCCCCCCCCCC

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.48
TSHR P16473 1/20 0.44
THRB P10828 1/20 0.44
SPHK1 Q9NYA1 1/20 0.44
LMNA P02545 1/20 0.44
DNM1 Q05193 2/20 0.43
ADH1B P00325 1/20 0.41
ADH1C P00326 1/20 0.41
ADH1A P07327 1/20 0.41
ADH4 P08319 1/20 0.41
ADH7 P40394 1/20 0.41
ACE2 Q9BYF1 1/20 0.40
FDPS P14324 3/20 0.39
GPR84 Q9NQS5 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10631973 1.00 OPRM1 (0.48) OPRM1TSHRTHRBSPHK1LMNA
SCHEMBL7628846 1.00 OPRM1 (0.48) OPRM1TSHRTHRBSPHK1LMNA
SCHEMBL8164513 1.00 OPRM1 (0.48) OPRM1TSHRTHRBSPHK1LMNA
SCHEMBL1598636 1.00 OPRM1 (0.48) OPRM1TSHRTHRBSPHK1LMNA
SCHEMBL10631876 1.00 OPRM1 (0.48) OPRM1TSHRTHRBSPHK1LMNA
SCHEMBL10631745 1.00 OPRM1 (0.48) OPRM1TSHRTHRBSPHK1LMNA
SCHEMBL8074389 0.97 OPRM1 (0.46) OPRM1TSHRTHRBSPHK1LMNA
SCHEMBL10634837 0.97 OPRM1 (0.50) OPRM1TSHRTHRBSPHK1LMNA
SCHEMBL23618041 0.90 OPRM1 (0.44) OPRM1TSHRTHRBSPHK1LMNA
Propene SCHEMBL27863126 0.89 ADH1B (0.39) OPRM1TSHRTHRBSPHK1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3320026-B1 SILOXANE CROSSLINKING PROCESSES EMPLOYING SULFUR COMPOUNDS AND PLATINUM CATALYSTS MOMENTIVE PERFORMANCE MAT INC (US) 2020-03-04 EP disclosed
US-10457795-B2 Siloxane crosslinking processes employing sulfur compounds and platinum catalysts MOMENTIVE PERFORMANCE MATERIALS, INC. (US) 2019-10-29 US disclosed
US-20180194931-A1 SILOXANE CROSSLINKING PROCESSES EMPLOYING SULFUR COMPOUNDS AND PLATINUM CATALYSTS MOMENTIVE PERFORMANCE MATERIALS INC. 2018-07-12 US disclosed
EP-3320026-A1 SILOXANE CROSSLINKING PROCESSES EMPLOYING SULFUR COMPOUNDS AND PLATINUM CATALYSTS Momentive Performance Materials Inc. (US) 2018-05-16 EP disclosed
WO-2017007512-A1 SILOXANE CROSSLINKING PROCESSES EMPLOYING SULFUR COMPOUNDS AND PLATINUM CATALYSTS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2017-01-12 WO disclosed
US-6184180-B1 COMPRISES SUPPORT, REVERSIBLE HEAT-SENSITIVE RECORDING LAYER CONTAINING DYE PRECURSOR WHICH IS COLORLESS OR A PALE COLOR, COLOR DEVELOPER CAPABLE OF CAUSING REVERSIBLE CHANGE IN COLOR DENSITY OF DYE DUE TO DIFFERENCE IN COOLING RATE MITSUBISHI PAPER MILLS LIMITED (JP) 2001-02-06 US disclosed
US-4020030-A CROSSLINKABLE THE DOW CHEMICAL COMPANY (US) 1977-04-26 US disclosed