Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.57 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23963281 | 0.86 | ADORA3 (0.56) | ADORA3ADORA2BRAB9ANPC1LMNA | |
| SCHEMBL23840696 | 0.85 | ADORA3 (0.64) | ADORA3ADORA2BRAB9ANPC1LMNA | |
| SCHEMBL9325911 | 0.75 | ADORA3 (0.62) | ADORA3ADORA2BRAB9ANPC1LMNA | |
| SCHEMBL9328560 | 0.73 | ADORA3 (0.58) | ADORA3ADORA2BRAB9ANPC1LMNA | |
| SCHEMBL23291195 | 0.73 | ADORA3 (0.58) | ADORA3ADORA2BRAB9ANPC1LMNA | |
| SCHEMBL9264847 | 0.73 | ADORA3 (1.00) | ADORA3ADORA2BKDM4EALDH1A1ADORA2A | |
| SCHEMBL30427750 | 0.73 | ADORA3 (0.58) | ADORA3ADORA2BRAB9ANPC1LMNA | |
| SCHEMBL11918984 | 0.72 | ADORA3 (0.52) | ADORA3ADORA2BRAB9ANPC1LMNA | |
| SCHEMBL9328945 | 0.69 | ADORA3 (0.64) | ADORA3ADORA2BRAB9ANPC1LMNA | |
| SCHEMBL22638180 | 0.68 | ADORA3 (0.62) | ADORA3ADORA2BRAB9ANPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2001011064-A | AROMATIC ALKANE DERIVATIVE | EISAI CO LTD | 2001-01-16 | — | — | JP | disclosed |