Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22890979 | 0.84 | POLB (0.55) | POLBNPC1RAB9ATAAR1GAA | |
| SCHEMBL19508785 | 0.81 | NPC1 (0.57) | POLBNPC1RAB9ATAAR1GAA | |
| SCHEMBL22500116 | 0.79 | KMT2A (0.57) | POLBNPC1RAB9ATAAR1GAA | |
| SCHEMBL828721 | 0.78 | NPC1 (0.54) | POLBNPC1RAB9ATAAR1GAA | |
| SCHEMBL2095490 | 0.77 | TAAR1 (0.69) | NPC1RAB9ATAAR1GAAHDAC3 | |
| SCHEMBL19509287 | 0.77 | NPC1 (0.54) | POLBNPC1RAB9ATAAR1GAA | |
| SCHEMBL158220 | 0.76 | HDAC3 (0.78) | POLBNPC1RAB9ATAAR1GAA | |
| SCHEMBL2095487 | 0.76 | NPC1 (0.58) | NPC1RAB9ATAAR1GAAHDAC3 | |
| SCHEMBL7750550 | 0.75 | RAB9A (0.49) | NPC1RAB9AGAAMAPTSMN1; SMN2 | |
| SCHEMBL12478845 | 0.75 | NPC1 (0.50) | NPC1RAB9ATAAR1GAAHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255120-B1 | HYDROXYAMIDES ATTACHED TO SOLID SUPPORT | PHARMACOPEIA, INC. | 2001-07-03 | — | — | US | claimed |