Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | KLK7 | P49862 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7751989 | 0.88 | HPGD (0.63) | RAB9ANPC1HPGDCRHBPCRHR2 | |
| SCHEMBL11019803 | 0.82 | LMNA (0.54) | RAB9AMEN1KMT2ANPC1HPGD | |
| SCHEMBL10639437 | 0.81 | RAB9A (0.50) | RAB9AKLK7MEN1KMT2ANPC1 | |
| SCHEMBL22372333 | 0.81 | HPGD (0.49) | RAB9AKLK7MEN1KMT2ANPC1 | |
| SCHEMBL28451128 | 0.80 | RAB9A (0.49) | RAB9AKLK7MEN1KMT2ANPC1 | |
| SCHEMBL11802080 | 0.79 | RAB9A (0.48) | RAB9AKLK7MEN1KMT2ANPC1 | |
| SCHEMBL24654619 | 0.78 | KLK7 (0.56) | RAB9AKLK7MEN1KMT2ANPC1 | |
| SCHEMBL22459216 | 0.78 | CTSK (0.48) | RAB9AKLK7MEN1KMT2ANPC1 | |
| Propham SCHEMBL8536412 | 0.77 | SMN1; SMN2 (0.66) | RAB9AKLK7MEN1KMT2ANPC1 | |
| Propham SCHEMBL67344 | 0.77 | SMN1; SMN2 (0.66) | RAB9AKLK7MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255120-B1 | HYDROXYAMIDES ATTACHED TO SOLID SUPPORT | PHARMACOPEIA, INC. | 2001-07-03 | — | — | US | claimed |