Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.42 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.41 |
| ▸ | MLNR | O43193 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7374300 | 0.95 | KMT2A (0.45) | GAAPOLBCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL7373839 | 0.95 | KMT2A (0.45) | GAAPOLBCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL7376733 | 0.95 | KMT2A (0.45) | GAAPOLBCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL7369738 | 0.94 | MEN1 (0.46) | GAAPOLBCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL7377924 | 0.91 | MEN1 (0.46) | GAAPOLBCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL7368737 | 0.90 | RAB9A (0.43) | GAAPOLBCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL7378099 | 0.89 | L3MBTL1 (0.43) | GAAPOLBCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL7342536 | 0.88 | KMT2A (0.44) | PPARDALDH1A1RAB9AKMT2AAVPR2 | |
| SCHEMBL7378419 | 0.88 | L3MBTL1 (0.42) | GAAPOLBCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL7373461 | 0.87 | RECQL (0.42) | GAAPOLBPPARGALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211242-B1 | CARDIOVASCULAR DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-0757670-B1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-01-13 | — | — | EP | disclosed |