Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | GABRP | O00591 | 2/20 | 0.30 |
| ▸ | GABRD | O14764 | 2/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.30 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.30 |
| ▸ | GABRE | P78334 | 2/20 | 0.30 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.30 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.30 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.30 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9533973 | 0.81 | CES2 (0.38) | CA1 | |
| SCHEMBL2530431 | 0.80 | CA1 (0.50) | CA1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL9531031 | 0.78 | — | — | |
| SCHEMBL9532328 | 0.77 | KMT2A (0.43) | CA1 | |
| SCHEMBL483277 | 0.72 | — | — | |
| SCHEMBL6179882 | 0.72 | — | — | |
| SCHEMBL1412935 | 0.72 | — | — | |
| SCHEMBL8588336 | 0.72 | — | — | |
| SCHEMBL2531343 | 0.71 | CA1 (0.41) | CA1 | |
| SCHEMBL28634340 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1071685-A4 | TITANIUM CATALYZED PREPARATION OF CARBAPENEM INTERMEDIATES | MERCK & CO INC (US) | 2001-07-18 | — | — | EP | disclosed |
| EP-1071685-A1 | TITANIUM CATALYZED PREPARATION OF CARBAPENEM INTERMEDIATES | Merck & Co., Inc. (US) | 2001-01-31 | — | — | EP | disclosed |
| WO-1999052908-A1 | TITANIUM CATALYZED PREPARATION OF CARBAPENEM INTERMEDIATES | MERCK & CO., INC. (US) | 1999-10-21 | — | — | WO | disclosed |