Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 3/20 | 0.42 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | IAPP | P10997 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9533973 | 0.86 | CES2 (0.38) | KMT2AMAPTCES1CES2ALDH1A1 | |
| SCHEMBL109369 | 0.82 | KMT2A (0.46) | KMT2AMAPTCES1CES2ALDH1A1 | |
| SCHEMBL8620850 | 0.80 | MAPT (0.45) | KMT2AMAPTCES1CES2ALDH1A1 | |
| SCHEMBL9532213 | 0.80 | CES1 (0.44) | KMT2AMAPTCES1CES2ALDH1A1 | |
| SCHEMBL9531031 | 0.79 | — | — | |
| Isopropyl Alcohol SCHEMBL4911456 | 0.79 | CES1 (0.52) | KMT2AMAPTCES1CES2ALDH1A1 | |
| SCHEMBL26103453 | 0.78 | ALDH1A1 (0.44) | KMT2AMAPTCES1CES2ALDH1A1 | |
| Ethylene SCHEMBL11685093 | 0.78 | CES1 (0.58) | KMT2AMAPTCES1CES2ALDH1A1 | |
| SCHEMBL106334 | 0.78 | CES1 (0.65) | KMT2AMAPTCES1CES2ALDH1A1 | |
| SCHEMBL27757367 | 0.78 | CES1 (0.65) | KMT2AMAPTCES1CES2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0555331-A1 | N-SUBSTITUTED IMIDAZOL-2-ONE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS. | SEARLE & CO (US) | 1993-08-18 | — | — | EP | disclosed |