Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAF1 | P04049 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7744995 | 0.90 | ALDH1A1 (0.39) | ALDH1A1VCAM1MAPTLMNARAF1 | |
| SCHEMBL7749462 | 0.90 | ALDH1A1 (0.43) | ALDH1A1VCAM1MAPTLMNARAF1 | |
| SCHEMBL7750945 | 0.84 | ALDH1A1 (0.42) | ALDH1A1VCAM1MAPTLMNARAF1 | |
| SCHEMBL4850984 | 0.80 | ALDH1A1 (0.47) | ALDH1A1VCAM1MAPTLMNAMAPK1 | |
| SCHEMBL4855450 | 0.80 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNA | |
| SCHEMBL187593 | 0.77 | ALDH1A1 (0.43) | ALDH1A1MAPTLMNAPKM | |
| SCHEMBL8769251 | 0.76 | ALDH1A1 (0.54) | ALDH1A1MAPTLMNARAF1HPGD | |
| SCHEMBL6881776 | 0.75 | ALDH1A1 (0.44) | ALDH1A1MAPTMAPK1PKM | |
| SCHEMBL7681081 | 0.75 | MAPT (0.46) | ALDH1A1MAPTLMNAMAPK1 | |
| SCHEMBL19371262 | 0.75 | ALDH1A1 (0.46) | ALDH1A1MAPTMAPK1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0781757-B1 | Process for the preparation of fluorinated benzoic acids | ABBOTT LAB (US) | 2001-01-03 | — | — | EP | disclosed |
| EP-0610384-B1 | PROCESS FOR THE PREPARATION OF FLUORINATED BENZOIC ACIDS | ABBOTT LAB (US) | 1997-09-03 | — | — | EP | disclosed |
| EP-0781757-A1 | Process for the preparation of fluorinated benzoic acids | ABBOTT LABORATORIES (US) | 1997-07-02 | — | — | EP | disclosed |
| US-5637765-A | Process for the preparation of fluorinated benzoic acids | ABBOTT LABORATORIES (US) | 1997-06-10 | — | — | US | disclosed |
| US-5633399-A | Process for the preparation of fluorinated benzoic acids | ABBOTT LABORATORIES (US) | 1997-05-27 | — | — | US | disclosed |
| US-5576455-A | Process for the preparation of fluorinated benzoic acids | ABBOTT LABORATORIES (US) | 1996-11-19 | — | — | US | disclosed |