Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 4/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2418512 | 0.76 | GABRP (0.42) | NOTUM | |
| SCHEMBL8339081 | 0.73 | KIF11 (0.41) | — | |
| SCHEMBL8306293 | 0.72 | MEN1 (0.39) | DYRK1A | |
| SCHEMBL8302686 | 0.71 | DYRK1A (0.35) | CDK5DYRK1ACDK5R1 | |
| SCHEMBL8399379 | 0.70 | NOTUM (0.36) | NOTUM | |
| SCHEMBL8551679 | 0.70 | — | — | |
| SCHEMBL7926453 | 0.64 | NOTUM (0.42) | NOTUM | |
| SCHEMBL20819066 | 0.64 | CDK5 (0.56) | CDK5DYRK1ACDK5R1GRM5 | |
| SCHEMBL7460779 | 0.63 | — | — | |
| SCHEMBL7957134 | 0.62 | GABRP (0.42) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1073627-A1 | PROCESSES FOR PREPARING PESTICIDAL INTERMEDIATES | AVENTIS AGRICULTURE LTD. (GB) | 2001-02-07 | — | — | EP | disclosed |
| WO-1999054288-A1 | PROCESSES FOR PREPARING PESTICIDAL INTERMEDIATES | AVENTIS AGRICULTURE LTD. (GB) | 1999-10-28 | — | — | WO | disclosed |