Fr-173657

Fr-173657

SCHEMBL29473494

CC(=O)Nc1ccc(/C=C/C(=O)NCC(=O)N(C)c2ccc(Cl)c(COc3cccc4ccc(C)nc34)c2Cl)cn1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
BDKRB2 P30411 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fr-173657 SCHEMBL1559539 1.00 BDKRB2 (1.00) BDKRB2
Fr-173657 SCHEMBL3718364 1.00 BDKRB2 (1.00) BDKRB2
Fr-173657 SCHEMBL7246238 0.99 BDKRB2 (0.99) BDKRB2
Fr-173657 SCHEMBL7246230 0.99 BDKRB2 (0.99) BDKRB2
SCHEMBL7742468 0.95 BDKRB2 (0.91) BDKRB2
SCHEMBL7742459 0.95 BDKRB2 (0.91) BDKRB2
SCHEMBL8812166 0.95 BDKRB2 (0.90) BDKRB2
SCHEMBL7749804 0.93 BDKRB2 (0.87) BDKRB2
SCHEMBL7748002 0.93 BDKRB2 (0.87) BDKRB2
SCHEMBL7749801 0.93 BDKRB2 (0.87) BDKRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260124192-A1 COMPOUNDS, COMPOSITIONS, AND METHODS OF TREATING RNA VIRAL INFECTIONS MODEL MEDICINES INC (US) 2026-05-07 US disclosed
US-20260102384-A1 USE OF PIPENDOXIFENE FOR TREATING INFECTIONS OF DNA VIRUSES MODEL MEDICINES INC (US) 2026-04-16 US disclosed
US-12551475-B2 Methods and compositions for treating RNA viral infections MODEL MEDICINES, INC. (US) 2026-02-17 US disclosed
EP-4667008-A2 METHODS AND COMPOSITIONS FOR TREATING RNA VIRAL INFECTIONS Model Medicines, Inc. (US) 2025-12-24 EP disclosed
US-20250025454-A1 USE OF PIPENDOXIFENE TO TREAT SARS-COV-2 INFECTION MODEL MEDICINES INC (US) 2025-01-23 US disclosed
US-20240082228-A1 SARS-COV-2 THERAPEUTICS MODEL MEDICINES INC (US) 2024-03-14 US disclosed
EP-4281180-A1 SARS-COV-2 THERAPEUTICS Model Medicines, Inc. (US) 2023-11-29 EP disclosed
US-20230346792-A1 COMPOSITIONS AND METHODS FOR TREATING LUNG INFLAMMATION HOTH THERAPEUTICS, INC. 2023-11-02 US disclosed
US-20230248712-A1 METHODS AND COMPOSITIONS FOR TREATING RNA VIRAL INFECTIONS MODEL MEDICINES, INC. 2023-08-10 US disclosed
EP-4157448-A1 METHODS AND COMPOSITIONS FOR TREATING RNA VIRAL INFECTIONS Model Medicines, Inc. (US) 2023-04-05 EP disclosed
CN-113330013-B Heterocyclic compound salt and application thereof 石药集团中奇制药技术(石家庄)有限公司 2022-12-27 CN disclosed
WO-2022159763-A1 SARS-COV-2 THERAPEUTICS MODEL MEDICINES, INC. (US) 2022-07-28 WO disclosed
US-20220098197-A1 SALTS OF HETEROCYCLIC COMPOUND AND USE THEREOF CSPC ZHONGQI PHARMACEUTICAL TECHNOLOGY (SHIJIAZHUANG) CO., LTD. (CN) 2022-03-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220098197-A1 SALTS OF HETEROCYCLIC COMPOUND AND USE THEREOF CXCL10, CXCL8, LITAF BDKRB2 500/4885
US-12551475-B2 Methods and compositions for treating RNA viral infections SARS1, EIF2AK2, SNRPE BDKRB2 3817/4885
US-20260102384-A1 USE OF PIPENDOXIFENE FOR TREATING INFECTIONS OF DNA VIRUSES ESR1, VDR, POLL BDKRB2 3961/4885
US-20260124192-A1 COMPOUNDS, COMPOSITIONS, AND METHODS OF TREATING RNA VIRAL INFECTIONS SARS1, NSUN2, NSUN3 BDKRB2 4562/4885
US-20250025454-A1 USE OF PIPENDOXIFENE TO TREAT SARS-COV-2 INFECTION EIF2AK2, ACE2, SARS1 BDKRB2 1857/4885
US-20230346792-A1 COMPOSITIONS AND METHODS FOR TREATING LUNG INFLAMMATION ACE2, TMPRSS2, VIPR1 BDKRB2 17/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.