Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 1/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.43 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7754766 | 0.89 | DRD2 (0.55) | DRD4ADRB2ADRB1HTR2CSIRT2 | |
| SCHEMBL615623 | 0.85 | NOTUM (0.61) | DRD4HTR2CSIRT2LMNANPC1 | |
| SCHEMBL27888907 | 0.84 | HTR2C (0.58) | DRD4HTR2CSIRT2LMNANPC1 | |
| SCHEMBL15784402 | 0.83 | DRD4 (0.57) | DRD4HTR2CSIRT2LMNANPC1 | |
| SCHEMBL853931 | 0.83 | HTR2C (0.57) | DRD4HTR2CSIRT2LMNANPC1 | |
| SCHEMBL25321827 | 0.81 | HTR2C (0.56) | DRD4HTR2CSIRT2LMNANPC1 | |
| SCHEMBL2845681 | 0.81 | HTR2C (0.61) | DRD4ADRB2ADRB1HTR2CSIRT2 | |
| SCHEMBL30475931 | 0.81 | HTR2C (0.56) | DRD4HTR2CSIRT2LMNANPC1 | |
| SCHEMBL2061374 | 0.80 | HPGD (0.47) | SIRT2LMNANPC1MAPTHTT | |
| SCHEMBL15108132 | 0.79 | NOTUM (0.69) | DRD4ADRB2ADRB1HTR2CNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0604278-B1 | Indoline derivatives and dye compositions for keratinic fibres | OREAL (FR) | 2001-02-21 | — | — | EP | claimed |