Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7749893 | 0.89 | DRD4 (0.55) | DRD2LMNANPC1MAPTHTT | |
| SCHEMBL981641 | 0.85 | NOTUM (0.60) | DRD2LMNANPC1MAPTHTT | |
| SCHEMBL27872558 | 0.84 | DRD2 (0.57) | DRD2LMNANPC1MAPTHTT | |
| SCHEMBL2203452 | 0.84 | DRD2 (0.58) | DRD2LMNANPC1MAPTHTT | |
| SCHEMBL3735431 | 0.83 | DRD2 (0.56) | DRD2LMNANPC1MAPTHTT | |
| SCHEMBL29962960 | 0.81 | DRD2 (0.52) | DRD2LMNANPC1MAPTHTT | |
| SCHEMBL29962149 | 0.81 | DRD2 (0.52) | DRD2LMNANPC1MAPTHTT | |
| SCHEMBL3318846 | 0.81 | DRD2 (0.52) | DRD2LMNANPC1MAPTHTT | |
| SCHEMBL2061374 | 0.80 | HPGD (0.47) | LMNANPC1MAPTHTTL3MBTL1 | |
| SCHEMBL8134006 | 0.79 | DRD2 (0.58) | DRD2LMNANPC1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0604278-B1 | Indoline derivatives and dye compositions for keratinic fibres | OREAL (FR) | 2001-02-21 | — | — | EP | claimed |
| US-5427588-A | Oxidation hair dyes; 1-oxy- or aminocarbonyl or oxy- or aminothiocarbonylindololines | L'OREAL (FR) | 1995-06-27 | — | — | US | claimed |
| EP-0604278-A1 | Indoline derivatives and dye compositions for keratinic fibres | L'OREAL (FR) | 1994-06-29 | — | — | EP | claimed |
| JP-6263730-A | — | — | None | — | — | JP | disclosed |
| EP-0604278-B1 | Indoline derivatives and dye compositions for keratinic fibres | OREAL (FR) | 2001-02-21 | — | — | EP | disclosed |
| US-5556989-A | HAIR DYES | L'OREAL (FR) | 1996-09-17 | — | — | US | disclosed |
| US-5534503-A | 2'-O, N6 -disubstituted and 2'-O, N6, 2-trisubstituted adenosines and their medicinal uses | SANDOZ LTD. (CH) | 1996-07-09 | — | — | US | disclosed |
| US-5427588-A | Oxidation hair dyes; 1-oxy- or aminocarbonyl or oxy- or aminothiocarbonylindololines | L'OREAL (FR) | 1995-06-27 | — | — | US | disclosed |
| JP-H06263730-A | NOVEL INDOLINE COMPOUND, DYEING COMPOSITION COMPRISING THIS COMPOUND AS BASE AND DYEING PROCESS OF KERATINOUS FIBER | L'OREAL SA | 1994-09-20 | — | — | JP | disclosed |
| EP-0604278-A1 | Indoline derivatives and dye compositions for keratinic fibres | L'OREAL (FR) | 1994-06-29 | — | — | EP | disclosed |