Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | CHUK | O15111 | 1/20 | 0.49 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.49 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NMT1 | P30419 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL432480 | 0.83 | NPC1 (0.53) | MAPK1NPC1RAB9ATDP1L3MBTL1 | |
| SCHEMBL10202922 | 0.77 | MAPK1 (0.54) | MAPK1NPC1RAB9ATDP1L3MBTL1 | |
| SCHEMBL2656622 | 0.77 | MAPK1 (0.61) | MAPK1NPC1RAB9ATDP1L3MBTL1 | |
| SCHEMBL92379 | 0.74 | MAPK1 (0.57) | MAPK1NPC1RAB9ATDP1L3MBTL1 | |
| SCHEMBL23455006 | 0.73 | SLC6A2 (0.39) | MAPK1NPC1RAB9ATDP1L3MBTL1 | |
| SCHEMBL433715 | 0.73 | MAPK1 (0.53) | MAPK1NPC1RAB9ATDP1L3MBTL1 | |
| SCHEMBL11867175 | 0.73 | CHUK (0.61) | MAPK1NPC1RAB9ATDP1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL12478356 | 0.72 | MAPK1 (0.53) | MAPK1NPC1RAB9ATDP1L3MBTL1 | |
| SCHEMBL9416867 | 0.72 | L3MBTL1 (0.53) | MAPK1NPC1RAB9ATDP1L3MBTL1 | |
| SCHEMBL13684208 | 0.72 | RAB9A (0.53) | MAPK1NPC1RAB9ATDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129415-B2 | Fungicide hydroximoyl-tetrazole derivatives | BAYER CROPSCIENCE AG (DE) | 2012-03-06 | — | — | US | disclosed |
| US-20090192196-A1 | Fungicide hydroximoyl-tetrazole derivatives | BAYER CROPSCIENCE AG (DE) | 2009-07-30 | — | — | US | disclosed |
| US-20080293674-A1 | Azinyl Imidazoazine and Azinyl Carboxamide | BAYER CROPSCIENCE AG (DE) | 2008-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293674-A1 | Azinyl Imidazoazine and Azinyl Carboxamide | AZI2, NISCH, ZYX | MAPK1 3570/4885NPC1 2845/4885RAB9A 4703/4885 |
| US-20090192196-A1 | Fungicide hydroximoyl-tetrazole derivatives | HAAO, HAO1, CYP51A1 | MAPK1 2712/4885NPC1 3856/4885RAB9A 3465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.