Methacrylic Acid

Methacrylic Acid

SCHEMBL7750591

C=C(C)C(=O)O.O=C(NCCO)c1cccnc1

nearest known ligand 0.61

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Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 8/20 0.60
MEN1 O00255 6/20 0.60
CYP1A2 P05177 1/20 0.60
CYP3A4 P08684 1/20 0.60
THRB P10828 1/20 0.60
RAB9A P51151 3/20 0.59
NPC1 O15118 3/20 0.59
SMN1; SMN2 Q16637 2/20 0.59
EPHX2 P34913 4/20 0.56
CYP2C9 P11712 2/20 0.56
CYP2C19 P33261 2/20 0.56
ALDH1A1 P00352 1/20 0.55
MAPT P10636 1/20 0.52
ALOX15 P16050 1/20 0.51
HSD17B10 Q99714 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
USP2 O75604 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30664046 0.89 THRB (0.75) KMT2AMEN1CYP1A2CYP3A4THRB
SCHEMBL62572 0.89 THRB (0.75) KMT2AMEN1CYP1A2CYP3A4THRB
Bromide SCHEMBL5671430 0.87 THRB (0.73) KMT2AMEN1CYP1A2CYP3A4THRB
Hydrochloric Acid SCHEMBL7321595 0.87 THRB (0.73) KMT2AMEN1CYP1A2CYP3A4THRB
SCHEMBL11523101 0.83 KMT2A (0.63) KMT2AMEN1CYP1A2CYP3A4THRB
SCHEMBL25328235 0.81 THRB (0.77) KMT2AMEN1CYP1A2CYP3A4THRB
Nitric Acid SCHEMBL4743268 0.81 MEN1 (0.67) KMT2AMEN1CYP1A2CYP3A4THRB
SCHEMBL7750576 0.80 KMT2A (0.78) KMT2AMEN1CYP1A2CYP3A4THRB
SCHEMBL3514768 0.80 THRB (0.71) KMT2AMEN1CYP1A2CYP3A4THRB
SCHEMBL2497123 0.78 THRB (0.68) KMT2AMEN1CYP1A2CYP3A4THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1075279-A2 SYNTHETIC POLYAMINOACID COMPLEXES FOR DELIVERY OF NUCLEIC ACIDS TO TARGET CELLS UNIVERSITEIT GENT (BE) 2001-02-14 EP disclosed
WO-1999058151-A2 SYNTHETIC POLYAMINOACID COMPLEXES FOR DELIVERY OF NUCLEIC ACIDS TO TARGET CELLS UNIVERSITEIT GENT (BE) 1999-11-18 WO disclosed