Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.68 |
| ▸ | MEN1 | O00255 | 4/20 | 0.68 |
| ▸ | RAB9A | P51151 | 4/20 | 0.68 |
| ▸ | NPC1 | O15118 | 3/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.68 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.58 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30664046 | 1.00 | THRB (0.75) | THRBKMT2AMEN1RAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL7321595 | 0.98 | THRB (0.73) | THRBKMT2AMEN1RAB9ANPC1 | |
| Bromide SCHEMBL5671430 | 0.98 | THRB (0.73) | THRBKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL25328235 | 0.91 | THRB (0.77) | THRBKMT2AMEN1RAB9ANPC1 | |
| Nitric Acid SCHEMBL4743268 | 0.91 | MEN1 (0.67) | THRBKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL3514768 | 0.90 | THRB (0.71) | THRBKMT2AMEN1RAB9ANPC1 | |
| Methacrylic Acid SCHEMBL7750591 | 0.89 | KMT2A (0.60) | THRBKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL9809561 | 0.88 | RAB9A (0.76) | THRBKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL17822214 | 0.88 | EPHX2 (0.75) | THRBKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL16323089 | 0.87 | THRB (0.67) | THRBKMT2AMEN1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 297 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119852298-A | Method for improving technological efficiency of sodium ion negative electrode dry pulping process | 浙江华宇钠电新能源科技有限公司 | 2025-04-18 | — | — | CN | claimed |
| CN-114621138-B | Nicorandil Synthesis method of trimer | 江苏天士力帝益药业有限公司 | 2024-12-31 | — | — | CN | claimed |
| CN-117706009-A | Method for detecting aminoethyl nitrate in nicorandil bulk drug | 上海旭东海普药业有限公司 | 2024-03-15 | — | — | CN | claimed |
| CN-114920691-B | Preparation method of N- (2-hydroxyethyl) nicotinamide and preparation method of nicorandil | 海口天行健药物研究有限公司 | 2024-03-08 | — | — | CN | claimed |
| CN-117486792-A | Nicotil intermediate and preparation method thereof | 北京四环科宝制药股份有限公司 | 2024-02-02 | — | — | CN | claimed |
| CN-116813540-A | Refining method of nicorandil intermediate | 上海旭东海普药业有限公司 | 2023-09-29 | — | — | CN | claimed |
| CN-116354878-A | Synthesis method of nicorandil | 长春大政药业科技有限公司 | 2023-06-30 | — | — | CN | claimed |
| CN-115745879-A | Synthesis method of nicorandil, nicorandil for injection and preparation method thereof | 海南皇隆制药股份有限公司 | 2023-03-07 | — | — | CN | claimed |
| CN-111269175-B | Nicorandil preparation method | 张家港九力新材料科技有限公司 | 2022-11-29 | — | — | CN | claimed |
| CN-114920691-A | Preparation method of N- (2-hydroxyethyl) nicotinamide and preparation method of nicorandil | 海口天行健药物研究有限公司 | 2022-08-19 | — | — | CN | claimed |
| WO-1991001331-A1 | SMALL CYCLIC PLATELET AGGREGATION INHIBITORS | GENENTECH, INC. (US) | 1991-02-07 | — | — | WO | claimed |
| EP-0333743-A1 | USE OF NICORANDIL TO TREAT ALOPECIA | THE UPJOHN COMPANY (US) | 1989-09-27 | — | — | EP | claimed |
| WO-1988004171-A1 | USE OF NICORANDIL TO TREAT ALOPECIA | THE UPJOHN COMPANY (US) | 1988-06-16 | — | — | WO | claimed |
| US-4680392-A | Substituted caprolactam derivatives as antihypertensives | MERCK & CO., INC. (US) | 1987-07-14 | — | — | US | claimed |
| EP-0198311-A2 | Nicotin amides and their use as fungicidal agents | F. HOFFMANN-LA ROCHE AG (CH) | 1986-10-22 | — | — | EP | claimed |
| US-4587050-A | Substituted enantholactam derivatives as antihypertensives | MERCK & CO., INC. (US) | 1986-05-06 | — | — | US | claimed |
| EP-0074584-B1 | PROLONGED-ACTION MULTIPLE-LAYER TABLETS | Chugai Seiyaku Kabushiki Kaisha (JP) | 1985-08-21 | — | — | EP | claimed |
| US-4454108-A | Prolonged-action multiple-layer tablets | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1984-06-12 | — | — | US | claimed |
| EP-0074584-A2 | Prolonged-action multiple-layer tablets | Chugai Seiyaku Kabushiki Kaisha (JP) | 1983-03-23 | — | — | EP | claimed |
| US-4200640-A | TREATING CIRCULATORY DISEASES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1980-04-29 | — | — | US | claimed |