Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | KMO | O15229 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ESRRG | P62508 | 2/20 | 0.31 |
| ▸ | ESRRB | O95718 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7755497 | 0.87 | ESR2 (0.37) | ESRRGESRRBESR1 | |
| SCHEMBL7756908 | 0.83 | ESRRG (0.35) | ALDH1A1LTA4HMRGPRX4HAO1NPC1 | |
| SCHEMBL7754641 | 0.83 | RARB (0.38) | ALDH1A1LTA4HKMT2A | |
| SCHEMBL7755527 | 0.82 | CYP2C9 (0.40) | ALDH1A1LTA4HMRGPRX4HAO1NPC1 | |
| SCHEMBL8077099 | 0.80 | POLB (0.35) | ALDH1A1L3MBTL1NPC1RAB9ACYP2D6 | |
| SCHEMBL7751125 | 0.80 | MRGPRX4 (0.37) | LTA4HMRGPRX4POLBKMT2A | |
| SCHEMBL7754659 | 0.80 | CYP2D6 (0.36) | LTA4HMRGPRX4DRD2CYP2D6ESRRG | |
| SCHEMBL8916794 | 0.76 | NPC1 (0.33) | ALDH1A1L3MBTL1NPC1RAB9APOLB | |
| SCHEMBL7752946 | 0.73 | POLB (0.31) | POLBKMT2A | |
| SCHEMBL10630480 | 0.73 | CYP2C9 (0.47) | ALDH1A1L3MBTL1MRGPRX4HAO1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708107-B1 | Novel silacyclohexane compounds, a liquid crystal composition comprising the same and a liquid crystal device comprising the composition | SHINETSU CHEMICAL CO (JP) | 2001-02-28 | — | — | EP | disclosed |
| US-5624601-A | Silacyclohexane compounds, a liquid crystal composition comprising the same and a liquid crystal device comprising the composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-04-29 | — | — | US | disclosed |
| EP-0708107-A1 | Novel silacyclohexane compounds, a liquid crystal composition comprising the same and a liquid crystal device comprising the composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-04-24 | — | — | EP | disclosed |