Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 9/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RARA | P10276 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7755527 | 0.91 | CYP2C9 (0.40) | CYP2C9ALDH1A1MAPTLTA4HLMNA | |
| SCHEMBL7756908 | 0.88 | ESRRG (0.35) | ALDH1A1LTA4H | |
| SCHEMBL7751125 | 0.86 | MRGPRX4 (0.37) | RARBTP53TSHRPLA2G4BMEN1 | |
| SCHEMBL7755480 | 0.86 | ESR2 (0.40) | CYP2C9KCNH2 | |
| SCHEMBL7754659 | 0.84 | CYP2D6 (0.36) | LTA4HKCNH2 | |
| SCHEMBL7750933 | 0.83 | ALDH1A1 (0.41) | ALDH1A1KMT2ALTA4H | |
| SCHEMBL8027799 | 0.82 | SPHK1 (0.37) | — | |
| SCHEMBL7754722 | 0.82 | ALDH1A1 (0.42) | RARBTP53TSHRCYP2C9ALDH1A1 | |
| SCHEMBL7754720 | 0.82 | ALDH1A1 (0.42) | RARBTP53TSHRCYP2C9ALDH1A1 | |
| SCHEMBL8581098 | 0.82 | ESR2 (0.36) | CYP2C9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708107-B1 | Novel silacyclohexane compounds, a liquid crystal composition comprising the same and a liquid crystal device comprising the composition | SHINETSU CHEMICAL CO (JP) | 2001-02-28 | — | — | EP | disclosed |
| US-5624601-A | Silacyclohexane compounds, a liquid crystal composition comprising the same and a liquid crystal device comprising the composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-04-29 | — | — | US | disclosed |
| EP-0708107-A1 | Novel silacyclohexane compounds, a liquid crystal composition comprising the same and a liquid crystal device comprising the composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-04-24 | — | — | EP | disclosed |