SCHEMBL7752946

SCHEMBL7752946

C=CCCC[Si]1(c2ccccc2)CCC(C2CCC(=O)CC2)CC1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8731015 0.86 LMNA (0.32)
SCHEMBL8449305 0.83 MEN1 (0.32) POLBKMT2A
SCHEMBL8916794 0.82 NPC1 (0.33) POLB
SCHEMBL7755593 0.82 KCNH2 (0.32) POLBKMT2A
SCHEMBL8451929 0.82
SCHEMBL8732796 0.81 KCNH2 (0.34) POLBKMT2A
SCHEMBL7756311 0.80
SCHEMBL7758954 0.80 ALDH1A1 (0.31)
SCHEMBL8077099 0.79 POLB (0.35) POLBKMT2A
SCHEMBL8449652 0.78 ALDH1A1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0696591-B1 Process for preparing silacyclohexane-based liquid crystal compounds SHINETSU CHEMICAL CO (JP) 2001-03-14 EP disclosed
EP-0687678-B1 Cyclohexanone compounds, process for preparing the same, and processes for preparing silacyclohexane-based liquid crystal compounds from the cyclohexanone compounds SHINETSU CHEMICAL CO (JP) 2000-03-22 EP disclosed
US-5730901-A Silacyclohexane compounds, preparation thereof liquid crystal compositions comprising the same, and liquid crystal devices comprising the composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 1998-03-24 US disclosed
US-5693841-A Cyclohexanone compounds, process for preparing the same, and processes for preparing silacyclohexane-based liquid crystal compounds from the cyclohexanone compounds SHIN-ETSU CHEMICAL CO., LTD. (JP) 1997-12-02 US disclosed
EP-0765880-A1 Process for preparing sil acyclohexane-based liquid crystal compounds from silacyclohexanone compounds SHIN-ETSU CHEMICAL CO., LTD. (JP) 1997-04-02 EP disclosed
EP-0742222-A2 Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 1996-11-13 EP disclosed
US-5514824-A Process for preparing silacyclohexane-base liquid crystal compounds SHIN-ETSU CHEMICAL CO., LTD. (JP) 1996-05-07 US disclosed
EP-0696591-A1 Process for preparing silacyclohexane-based liquid crystal compounds SHIN-ETSU CHEMICAL CO., LTD. (JP) 1996-02-14 EP disclosed
EP-0687678-A1 Cyclohexanone compounds, process for preparing the same, and processes for preparing silacyclohexane-based liquid crystal compounds from the cyclohexanone compounds SHIN-ETSU CHEMICAL CO., LTD. (JP) 1995-12-20 EP disclosed