Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 7/20 | 0.61 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.53 |
| ▸ | CYP24A1 | Q07973 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 3/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.40 |
| ▸ | CYP27A1 | Q02318 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7750942 | 0.88 | CYP26A1 (0.74) | CYP26A1CYP19A1CYP24A1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7750978 | 0.81 | CYP26A1 (0.58) | CYP26A1CYP19A1CYP24A1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8158688 | 0.77 | CYP26A1 (0.86) | CYP26A1CYP19A1CYP24A1ALDH1A1SMN1; SMN2 | |
| SCHEMBL14061950 | 0.74 | CYP26A1 (0.67) | CYP26A1CYP19A1CYP24A1 | |
| SCHEMBL7749818 | 0.73 | CYP26A1 (0.71) | CYP26A1CYP19A1CYP24A1ALDH1A1MAPT | |
| SCHEMBL20809677 | 0.71 | CYP26A1 (0.82) | CYP26A1CYP19A1CYP24A1ESR1ESR2 | |
| SCHEMBL4622497 | 0.71 | CYP26A1 (0.70) | CYP26A1CYP19A1CYP24A1 | |
| SCHEMBL7750981 | 0.71 | CYP26A1 (0.45) | CYP26A1CYP19A1CYP24A1CYP1A2MAPT | |
| SCHEMBL6300061 | 0.70 | CYP26A1 (0.61) | CYP26A1CYP19A1CYP24A1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8199307 | 0.70 | CYP26A1 (0.55) | CYP26A1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001042181-A1 | BENZYL TETRALINS, FORMULATIONS AND USES THEREOF | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2001-06-14 | — | — | WO | disclosed |