Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 7/20 | 0.82 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.71 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.63 |
| ▸ | ESR1 | P03372 | 6/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20809838 | 0.88 | CYP19A1 (0.68) | CYP26A1CYP19A1CYP24A1ESR2 | |
| SCHEMBL20809675 | 0.87 | CYP26A1 (0.73) | CYP26A1CYP19A1CYP24A1ESR1ESR2 | |
| SCHEMBL8158688 | 0.87 | CYP26A1 (0.86) | CYP26A1CYP19A1CYP24A1ESR1ESR2 | |
| SCHEMBL8203668 | 0.83 | CYP26A1 (0.79) | CYP26A1CYP19A1CYP24A1ITGB3ITGA2B | |
| SCHEMBL20809470 | 0.81 | CYP26A1 (0.64) | CYP26A1CYP19A1CYP24A1ESR1ESR2 | |
| SCHEMBL7750942 | 0.80 | CYP26A1 (0.74) | CYP26A1CYP19A1CYP24A1ESR1ESR2 | |
| SCHEMBL22105128 | 0.80 | CYP26A1 (0.62) | CYP26A1CYP19A1CYP24A1ESR1ESR2 | |
| SCHEMBL20809676 | 0.80 | CYP26A1 (0.62) | CYP26A1CYP19A1CYP24A1ESR1ESR2 | |
| SCHEMBL20809710 | 0.80 | CYP26A1 (0.62) | CYP26A1CYP19A1CYP24A1ESR1ESR2 | |
| SCHEMBL4622497 | 0.80 | CYP26A1 (0.70) | CYP26A1CYP19A1CYP24A1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11091421-B2 | Benzene fused heterocyclic derivative and pharmaceutical composition comprising the same | TAIWANJ PHARMACEUTICALS CO., LTD. (TW) | 2021-08-17 | — | — | US | disclosed |
| US-20200190010-A1 | BENZENE FUSED HETEROCYCLIC DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | TAIWANJ PHARMACEUTICALS CO., LTD. (TW) | 2020-06-18 | — | — | US | disclosed |
| WO-2019051222-A1 | BENZENE FUSED HETEROCYCLIC DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | TAIWANJ PHARMACEUTICALS CO., LTD. (TW) | 2019-03-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11091421-B2 | Benzene fused heterocyclic derivative and pharmaceutical composition comprising the same | RORB, RORC, NR3C1 | CYP26A1 418/4885CYP19A1 224/4885CYP24A1 262/4885 |
| US-20200190010-A1 | BENZENE FUSED HETEROCYCLIC DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | RORB, RORC, NR3C1 | CYP26A1 418/4885CYP19A1 224/4885CYP24A1 262/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.