Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 2/20 | 0.32 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.32 |
| ▸ | GRM8 | O00222 | 1/20 | 0.31 |
| ▸ | GRM6 | O15303 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1879279 | 0.92 | CYP2C19 (0.35) | GRM8GRM6GRM2GRM3CYP2C19 | |
| SCHEMBL4853650 | 0.72 | — | — | |
| SCHEMBL9700492 | 0.71 | EGLN1 (0.33) | GRM8GRM6GRM2GRM3CYP2C19 | |
| SCHEMBL30037802 | 0.70 | MCL1 (0.33) | GRM8GRM6GRM2GRM3ALDH1A1 | |
| SCHEMBL27761884 | 0.69 | TLR4 (0.34) | ALDH1A1 | |
| SCHEMBL27771250 | 0.69 | TLR4 (0.34) | ALDH1A1 | |
| SCHEMBL190832 | 0.69 | TLR4 (0.34) | ALDH1A1 | |
| SCHEMBL3974963 | 0.67 | KMT2A (0.36) | — | |
| SCHEMBL11378401 | 0.66 | AKR1C4 (0.39) | — | |
| SCHEMBL9541416 | 0.66 | CA1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120070353-A1 | Process For Separating Off Acidic Gases By Means Of Metal-Organic Frameworks Impregnated With Amines | BASF SE (DE) | 2012-03-22 | — | — | US | disclosed |