Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.55 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.53 |
| ▸ | BACE1 | P56817 | 2/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | F2R | P25116 | 1/20 | 0.46 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.46 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.46 |
| ▸ | CDK8 | P49336 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | WRN | Q14191 | 1/20 | 0.45 |
| ▸ | AKT1 | P31749 | 1/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9892896 | 0.84 | TSHR (0.63) | ARGRM4KDRMEN1NPC1 | |
| SCHEMBL4006280 | 0.84 | GRM4 (0.57) | ARGRM4KDRKCNJ5KCNJ3 | |
| SCHEMBL7752723 | 0.83 | MAPT (0.59) | KDRF2RKCNJ5KCNJ3MEN1 | |
| SCHEMBL1904289 | 0.80 | AR (0.64) | ARGRM4KDRPDK1CDK8 | |
| SCHEMBL8138993 | 0.80 | AR (0.50) | ARGRM4KDRKCNJ5KCNJ3 | |
| SCHEMBL8530877 | 0.79 | AR (0.58) | ARGRM4KDRCDK8BLM | |
| SCHEMBL463590 | 0.79 | AR (0.62) | ARGRM4KDRCDK8BLM | |
| SCHEMBL20560568 | 0.79 | GRM4 (0.61) | ARGRM4KDRPDK1CDK8 | |
| SCHEMBL31356647 | 0.79 | AR (0.58) | ARGRM4KDRCDK8BLM | |
| SCHEMBL1380778 | 0.79 | AR (0.58) | ARGRM4KDRCDK8BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0597304-B1 | Use of substituted benzimidazoles for combating parasitic protozoas | BAYER AG (DE) | 2001-01-10 | — | — | EP | disclosed |
| US-5877195-A | INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-03-02 | — | — | US | disclosed |
| EP-0667863-B1 | 2-PERHALOGENALKYL-SUBSTITUTED BENZIMIDAZOLES, THEIR PREPARATION AND THEIR USE AS PESTICIDES | BAYER AG (DE) | 1998-06-03 | — | — | EP | disclosed |
| US-5585395-A | INSECTICIDES, MITICIDES, FUNGICIDES, HERBICIDES, PLANT GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-12-17 | — | — | US | disclosed |
| US-5482956-A | ANTIPROTOZOA AGENTS FOR ANIMALS OR INSECTS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-01-09 | — | — | US | disclosed |
| EP-0667862-A1 | 2-FLUOROALKYL-SUBSTITUTED BENZIMIDAZOLES, THEIR PREPARATION AND THEIR USE AS PESTICIDES | BAYER AG (DE) | 1995-08-23 | — | — | EP | disclosed |
| EP-0667863-A1 | 2-PERHALOGENALKYL-SUBSTITUTED BENZIMIDAZOLES, THEIR PREPARATION AND THEIR USE AS PESTICIDES | BAYER AG (DE) | 1995-08-23 | — | — | EP | disclosed |
| EP-0667861-A1 | 2-FLUOROALKYL-SUBSTITUTED BENZIMIDAZOLES, THEIR PREPARATION AND THEIR USE AS PESTICIDES | BAYER AG (DE) | 1995-08-23 | — | — | EP | disclosed |
| WO-1994011351-A1 | 2-PERHALOGENALKYL-SUBSTITUTED BENZIMIDAZOLES, THEIR PREPARATION AND THEIR USE AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1994-05-26 | — | — | WO | disclosed |
| WO-1994011352-A1 | 2-CYANO-SUBSTITUTED BENZIMIDAZOLES, THEIR PRODUCTION AND THEIR USE AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1994-05-26 | — | — | WO | disclosed |
| WO-1994011350-A1 | 2-FLUOROALKYL-SUBSTITUTED BENZIMIDAZOLES, THEIR PREPARATION AND THEIR USE AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1994-05-26 | — | — | WO | disclosed |
| WO-1994011349-A1 | 2-FLUOROALKYL-SUBSTITUTED BENZIMIDAZOLES, THEIR PREPARATION AND THEIR USE AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1994-05-26 | — | — | WO | disclosed |