SCHEMBL7752013

SCHEMBL7752013

CCc1cccc2cccc(C)c12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.44
GABRB2 P47870 4/20 0.44
ELANE P08246 3/20 0.44
CYP1A2 P05177 2/20 0.41
ALDH1A1 P00352 3/20 0.40
CYP3A4 P08684 2/20 0.40
HPGD P15428 2/20 0.40
TSHR P16473 2/20 0.40
HSD17B10 Q99714 2/20 0.40
TDP1 Q9NUW8 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
CYP2A6 P11509 1/20 0.39
CYP1B1 Q16678 2/20 0.38
GPR84 Q9NQS5 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
NSD2 O96028 1/20 0.38
CASP6 P55212 1/20 0.38
GFER P55789 1/20 0.38
CYP1A1 P04798 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formaldehyde SCHEMBL28028377 0.96 ELANE (0.42) GABRA1GABRB2ELANECYP1A2ALDH1A1
SCHEMBL19198142 0.91 ELANE (0.42) GABRA1GABRB2ELANECYP1A2ALDH1A1
SCHEMBL3244580 0.85 GABRA1 (0.52) GABRA1GABRB2ELANECYP1A2ALDH1A1
SCHEMBL7823035 0.83 HTR2A (0.41) ELANECYP1A2ALDH1A1CYP3A4HPGD
SCHEMBL3283526 0.80 ELANE (0.41) GABRA1GABRB2ELANECYP1A2ALDH1A1
SCHEMBL15847863 0.80 ALDH1A1 (0.39) GABRA1GABRB2CYP1A2ALDH1A1CYP3A4
SCHEMBL3834629 0.80 ALDH1A1 (0.43) CYP1A2ALDH1A1CYP3A4HPGDTSHR
SCHEMBL15345424 0.80 TAAR1 (0.43) CYP1A2ALDH1A1CYP3A4HPGDTSHR
SCHEMBL3441851 0.78 GABRA1 (0.52) GABRA1GABRB2ELANECYP1A2ALDH1A1
SCHEMBL5248752 0.78 CYP1A2 (0.42) GABRA1GABRB2ELANECYP1A2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4223761-A1 QUINAZOLINE COMPOUND AND APPLICATION THEREOF Shanghai Pharmaceuticals Holding Co., Ltd. (CN) 2023-08-09 EP disclosed
WO-2021023247-A1 KRAS MUTANT PROTEIN INHIBITOR JACOBIO PHARMACEUTICALS CO., LTD. (CN) 2021-02-11 WO disclosed
CN-103242322-A Indolocarbazole derivative and application thereof to electroluminescent device UNIV JILIN 2013-08-14 CN disclosed
EP-0710684-B1 Preparation process of polyhydroxycarboxylic acid MITSUI CHEMICALS INC (JP) 2001-01-31 EP disclosed
US-5770683-A Preparation process of polyhydroxycarboxylic acid MITSUI TOATSU CHEMICALS, INC. (JP) 1998-06-23 US disclosed
EP-0710684-A2 Preparation process of polyhydroxycarboxylic acid MITSUI TOATSU CHEMICALS, Inc. (JP) 1996-05-08 EP disclosed