Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.47 |
| ▸ | GRM3 | Q14832 | 3/20 | 0.47 |
| ▸ | GRM8 | O00222 | 3/20 | 0.47 |
| ▸ | GRM6 | O15303 | 3/20 | 0.47 |
| ▸ | ARG1 | P05089 | 3/20 | 0.46 |
| ▸ | ARG2 | P78540 | 2/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 6/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | PLCB1 | Q9NQ66 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4311566 | 1.00 | SLC6A4 (0.48) | SLC6A4GRM2GRM3GRM8GRM6 | |
| SCHEMBL4831160 | 1.00 | SLC6A4 (0.48) | SLC6A4GRM2GRM3GRM8GRM6 | |
| SCHEMBL4831107 | 1.00 | SLC6A4 (0.48) | SLC6A4GRM2GRM3GRM8GRM6 | |
| SCHEMBL4840309 | 1.00 | SLC6A4 (0.48) | SLC6A4GRM2GRM3GRM8GRM6 | |
| SCHEMBL26332225 | 0.93 | SLC6A4 (0.47) | SLC6A4GRM2GRM3GRM8GRM6 | |
| SCHEMBL4835740 | 0.93 | SLC6A4 (0.47) | SLC6A4GRM2GRM3GRM8GRM6 | |
| SCHEMBL4835859 | 0.93 | SLC6A4 (0.47) | SLC6A4GRM2GRM3GRM8GRM6 | |
| SCHEMBL28580076 | 0.84 | ARG1 (0.45) | SLC6A4GRM2GRM3GRM8GRM6 | |
| SCHEMBL1939579 | 0.80 | GRM2 (0.36) | SLC6A4GRM2GRM3GRM8GRM6 | |
| SCHEMBL14662849 | 0.79 | SLC6A4 (0.43) | SLC6A4GRM2GRM3GRM8GRM6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5646132-A | TREATING CEREBRAL ISCHEMIA | ADIR ET COMPAGNIE (FR) | 1997-07-08 | — | — | US | disclosed |
| US-5536709-A | INHIBITORS OF HYPERACTIVATION OF EXCITATORY AMINO ACIDS | ADIR ET COMPAGNIE (FR) | 1996-07-16 | — | — | US | disclosed |