Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7755414 | 1.00 | ALDH1A1 (0.48) | ALDH1A1CA2TDP1LMNACYP3A4 | |
| SCHEMBL7752092 | 0.98 | ALDH1A1 (0.47) | ALDH1A1CA2TDP1LMNACYP3A4 | |
| SCHEMBL7756102 | 0.90 | LMNA (0.45) | ALDH1A1CA2TDP1LMNACYP3A4 | |
| SCHEMBL7755423 | 0.90 | ALDH1A1 (0.40) | ALDH1A1CA2TDP1LMNACYP3A4 | |
| SCHEMBL11440726 | 0.90 | LMNA (0.54) | LMNAGPR84 | |
| SCHEMBL3771381 | 0.90 | ALDH1A1 (0.54) | ALDH1A1CA2TDP1LMNACYP3A4 | |
| SCHEMBL9074800 | 0.90 | LMNA (0.54) | LMNAGPR84 | |
| SCHEMBL7754815 | 0.88 | ALDH1A1 (0.39) | ALDH1A1CA2TDP1LMNACYP3A4 | |
| SCHEMBL7754809 | 0.88 | ALDH1A1 (0.39) | ALDH1A1CA2TDP1LMNACYP3A4 | |
| SCHEMBL7752149 | 0.88 | LMNA (0.48) | ALDH1A1CA2LMNAGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0764636-B1 | Thiopropionate synergists | GOODYEAR TIRE & RUBBER (US) | 2001-03-07 | — | — | EP | disclosed |
| US-5672730-A | OXIDATION RESIST STABILIZER FOR POLYMERIC BLENDS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-09-30 | — | — | US | disclosed |
| EP-0764636-A2 | Thiopropionate synergists | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-03-26 | — | — | EP | disclosed |