Uridine

Uridine

SCHEMBL7752140

O=c1ccn([C@@H]2O[C@@H](CO)[C@H](O)[C@H]2O)c(=O)[nH]1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ SLC28A1 O00337 1/20 1.00
▸ SLC28A2 O43868 1/20 1.00
▸ SLC29A1 Q99808 1/20 1.00
▸ SLC28A3 Q9HAS3 1/20 1.00
▸ P2RY2 P41231 11/20 0.69
▸ P2RY6 Q15077 8/20 0.65
▸ P2RY4 P51582 4/20 0.63
▸ P2RY14 Q15391 7/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Uridine SCHEMBL14853938 1.00 SLC28A1 (1.00) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL2056533 1.00 SLC28A1 (1.00) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL329746 1.00 SLC28A1 (1.00) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL10815678 1.00 SLC28A1 (1.00) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL2056827 1.00 SLC28A1 (1.00) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL9060684 1.00 SLC28A1 (1.00) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL375985 1.00 SLC28A1 (1.00) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Arauridine SCHEMBL359587 1.00 SLC28A1 (1.00) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL20987631 1.00 SLC28A1 (1.00) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL1804774 1.00 SLC28A1 (1.00) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6242428-B1 NUCLEOSIDES AND NUCLEOSIDE DIMERS CONTAINING AN L-SUGAR IN AT LEAST ONE OF THE NUCLEOSIDES UNISEARCH LIMITED (AU) 2001-06-05 — — US disclosed
US-6207649-B1 DINUCLEOSIDE DIMERS AND DERIVATIVES INCLUDING L-DEOXYRIBOFURANOSYL NUCLEOSIDE PHOSPHODIESTER DIMERS IN WHICH SUGAR MOIETY OF ONE OF THE NUCLEOSIDES HAS AN L-CONFIGURATION; TREATMENT OF BACTERIAL, VIRAL, AND FUNGAL INFECTIONS, CANCER LIPITEK INTERNATIONAL, INC. 2001-03-27 — — US disclosed
EP-1069903-A1 NOVEL NUCLEOSIDE ANALOGS AND USES IN TREATING DISEASE Lipitek International, Inc. (US) 2001-01-24 — — EP disclosed
US-6025335-A L-DEOXYRIBOFURANOSYL NUCLEOSIDE PHOSPHODIESTER DIMERS WHERE THE SUGAR MOIETY OR AT LEAST ONE OF THE NUCLEOSIDES HAS AN L-CONFIGURATION, CANCER AND VIRAL INFECTIONS, IN MAMMALS. LIPITEK INTERNATIONAL, INC. (US) 2000-02-15 — — US disclosed
WO-1999045935-A1 NOVEL NUCLEOSIDE ANALOGS AND USES IN TREATING DISEASE LIPITEK INTERNATIONAL, INC. (US) 1999-09-16 — — WO disclosed
US-5939402-A TREATING PLASMODIUM, VIRAL INFECTIONS OR PARASITES IN MAMMALS LIPITEK INTERNATIONAL, INC. (US) 1999-08-17 — — US disclosed
EP-0793669-A4 L-NUCLEOSIDE DIMER COMPOUNDS AND THERAPEUTIC USES LIPITEK INTERNATIONAL INC (US) 1999-02-03 — — EP disclosed
EP-0793669-A1 L-NUCLEOSIDE DIMER COMPOUNDS AND THERAPEUTIC USES Lipitek International, Inc. (US) 1997-09-10 — — EP disclosed
WO-1997011087-A1 L-NUCLEOSIDE DIMER COMPOUNDS AND THERAPEUTIC USES LIPITEK INTERNATIONAL, INC. (US) 1997-03-27 — — WO disclosed
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