Uridine

Uridine

SCHEMBL2056827

O=c1ccn(C2OC(CO)C(O)C2O)c(=O)[nH]1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ SLC28A1 O00337 1/20 1.00
▸ SLC28A2 O43868 1/20 1.00
▸ SLC29A1 Q99808 1/20 1.00
▸ SLC28A3 Q9HAS3 1/20 1.00
▸ P2RY2 P41231 11/20 0.69
▸ P2RY6 Q15077 8/20 0.65
▸ P2RY4 P51582 4/20 0.63
▸ P2RY14 Q15391 7/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Uridine SCHEMBL14853938 1.00 SLC28A1 (1.00) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL2056533 1.00 SLC28A1 (1.00) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL329746 1.00 SLC28A1 (1.00) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL10815678 1.00 SLC28A1 (1.00) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL9060684 1.00 SLC28A1 (1.00) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL375985 1.00 SLC28A1 (1.00) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Arauridine SCHEMBL359587 1.00 SLC28A1 (1.00) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL7752140 1.00 SLC28A1 (1.00) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL20987631 1.00 SLC28A1 (1.00) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL1804774 1.00 SLC28A1 (1.00) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250295611-A1 METHODS OF TREATING 5HT2A RECEPTOR-MEDIATED CONDITIONS TESSELLATE THERAPEUTICS INC (US) 2025-09-25 — — US claimed
US-20250170149-A1 NEUROACTIVE STEROIDS FOR TREATMENT OF GASTROINTESTINAL DISEASES OR CONDITIONS SAGE THERAPEUTICS, INC. 2025-05-29 — — US claimed
US-20250170147-A1 NEUROACTIVE STEROIDS FOR TREATMENT OF GASTROINTESTINAL DISEASES OR CONDITIONS SAGE THERAPEUTICS, INC. 2025-05-29 — — US claimed
US-20250170148-A1 NEUROACTIVE STEROIDS FOR TREATMENT OF GASTROINTESTINAL DISEASES OR CONDITIONS SAGE THERAPEUTICS, INC. 2025-05-29 — — US claimed
EP-4479032-A1 NEUROACTIVE STEROIDS FOR TREATMENT OF CNS-RELATED DISORDERS Sage Therapeutics, Inc. (US) 2024-12-25 — — EP claimed
CN-119072304-A Neuroactive steroids for the treatment of CNS related disorders 萨奇治疗股份有限公司 2024-12-03 — — CN claimed
CN-118491503-A Artificial nuclease and preparation method and detection method thereof 天津大学 2024-08-16 — — CN claimed
WO-2023212244-A1 METHODS OF TREATING 5HT2A RECEPTOR-MEDIATED CONDITIONS TESSELLATE THERAPEUTICS, INC. (US) 2023-11-02 — — WO claimed
CN-116981450-A Combination of antidepressants and dextromethorphan for the treatment of neuropsychiatric disorders 安泰赛普生物风投二代有限责任公司 2023-10-31 — — CN claimed
WO-2023163879-A1 NEUROACTIVE STEROIDS FOR TREATMENT OF GASTROINTESTINAL DISEASES OR CONDITIONS SAGE THERAPEUTICS, INC. (US) 2023-08-31 — — WO claimed
WO-2023164386-A1 NEUROACTIVE STEROIDS FOR TREATMENT OF GASTROINTESTINAL DISEASES OR CONDITIONS SAGE THERAPEUTICS, INC. (US) 2023-08-31 — — WO claimed
WO-2023164387-A1 NEUROACTIVE STEROIDS FOR TREATMENT OF GASTROINTESTINAL DISEASES OR CONDITIONS SAGE THERAPEUTICS, INC. (US) 2023-08-31 — — WO claimed
WO-2023164385-A1 NEUROACTIVE STEROIDS FOR TREATMENT OF GASTROINTESTINAL DISEASES OR CONDITIONS SAGE THERAPEUTICS, INC. (US) 2023-08-31 — — WO claimed
WO-2023158668-A1 NEUROACTIVE STEROIDS FOR TREATMENT OF CNS-RELATED DISORDERS SAGE THERAPEUTICS, INC. (US) 2023-08-24 — — WO claimed
WO-2023159035-A1 NEUROACTIVE STEROIDS FOR TREATMENT OF CNS-RELATED DISORDERS SAGE THERAPEUTICS, INC. (US) 2023-08-24 — — WO claimed
US-20220146492-A1 CELL MEMBRANE PERMEABILITY RESTORING THERAPY SHINE IAN BASIL (US) 2022-05-12 — — US claimed
EP-3953000-A1 CELL MEMBRANE PERMEABILITY RESTORING THERAPY Shine, Ian Basil (US) 2022-02-16 — — EP claimed
US-20260097062-A1 AQUEOUS SOLUTIONS CONTAINING PURINES AND PYRIMIDINES AND USES THEREOF UCB BIOSCIENCES INC (US) 2026-04-09 — — US disclosed
US-20070179112-A1 POLYMERIC NUCLEOSIDE PRODRUGS RELIABLE BIOPHARMACEUTICAL, INC. (US) 2007-08-02 — — US disclosed
US-20070179112-A1 POLYMERIC NUCLEOSIDE PRODRUGS RELIABLE BIOPHARMACEUTICAL, INC. (US) 2007-08-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260097062-A1 AQUEOUS SOLUTIONS CONTAINING PURINES AND PYRIMIDINES AND USES THEREOF POLG, POLRMT, TK2 SLC28A1 1326/4885SLC28A2 676/4885SLC29A1 641/4885
US-20250170147-A1 NEUROACTIVE STEROIDS FOR TREATMENT OF GASTROINTESTINAL DISEASES OR CONDITIONS MC2R, CRH, NTSR2 SLC28A1 1486/4885SLC28A2 1099/4885SLC29A1 3639/4885
US-20250170149-A1 NEUROACTIVE STEROIDS FOR TREATMENT OF GASTROINTESTINAL DISEASES OR CONDITIONS MC2R, CRH, NTSR2 SLC28A1 1486/4885SLC28A2 1099/4885SLC29A1 3639/4885
US-20070179112-A1 POLYMERIC NUCLEOSIDE PRODRUGS TYMP, PNP, PAICS SLC28A1 122/4885SLC28A2 139/4885SLC29A1 22/4885
US-20250295611-A1 METHODS OF TREATING 5HT2A RECEPTOR-MEDIATED CONDITIONS HTR2A, HTR5A, HTR6 SLC28A1 863/4885SLC28A2 478/4885SLC29A1 1853/4885
US-20250170148-A1 NEUROACTIVE STEROIDS FOR TREATMENT OF GASTROINTESTINAL DISEASES OR CONDITIONS MC2R, CRH, NTSR2 SLC28A1 1486/4885SLC28A2 1099/4885SLC29A1 3639/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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